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Published TCIMAIL newest issue No.197
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CAS RN: 153-61-7 | Product Number: C2769
Cephalothin
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Purity: >98.0%(T)(HPLC)
Synonyms:
- Cephalotin
- 7-(2-Thienylacetamido)cephalosporanic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
36,00 €
|
2 | 9 |
|
| 25G |
137,00 €
|
2 | 4 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Supplemental Product Information:
This product has not been tested for potency and is guaranteed for chemical purity.
| Product Number | C2769 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__6N__2O__6S__2 = 396.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 153-61-7 |
| Reaxys Registry Number | 945586 |
| PubChem Substance ID | 253659770 |
| Merck Index (14) | 1982 |
| MDL Number | MFCD00242614 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 154 °C(dec.) |
| Maximum Absorption Wavelength | 263(H2O) nm |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| Precautionary Statements | P261 : Avoid breathing dust. P280 : Wear protective gloves. P284 : Wear respiratory protection. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 205-815-7 |
| RTECS# | XI0388000 |
Transport Information:
| HS Number | 2941900000 |
Application
Cephalothin: A First-Generation Cephalosporin Antibiotic
Cephalothin or cefalotin is a first-generation semisynthetic cephalosporin antibiotic, which is chemically synthesized form 7-aminocephalosporanic acid (7-ACA) [A1266], has been used worldwide since the mid-1960s. It has a broad spectrum of activity against Gram-positive and Gram-negative bacteria.
References
- Laboratory and Clinical Evaluation of a New Antibiotic―Cephalothin
- Cefoxitin and cephalothin: antimicrobial activity, human pharmacokinetics, and toxicology
- In vitro comparison of cefoxitin, cefamandole, cephalexin, and cephalothin
- Structural Milestones in the Reaction Pathway of an Amide Hydrolase Substrate, Acyl, and Product Complexes of Cephalothin with AmpC β-Lactamase
- Acyl-Intermediate Structures of the Extended-spectrum Class A β-Lactamase, Toho-1, in Complex with Cefotaxime, Cephalothin, and Benzylpenicillin
- Molecular Dynamics Simulations of the TEM-1 β-Lactamase Complexed with Cephalothin
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