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CAS RN: 128794-94-5 | Product Number: M2387
Mycophenolate Mofetil
Purity: >98.0%(T)(HPLC)
Synonyms:
- 2-(4-Morpholinyl)ethyl (E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoate
- (E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid 2-(4-Morpholinyl)ethyl Ester
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time | Shipping Information |
---|---|---|---|---|---|
100MG |
$18.00
|
28 | 6 | Contact Us | |
1G |
$91.00
|
33 | ≥100 | Contact Us |
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* The storage conditions are subject to change without notice.
Product Number | M2387 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__2__3H__3__1NO__7 = 433.50 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 128794-94-5 |
Reaxys Registry Number | 14419508 |
PubChem Substance ID | 253661600 |
Merck Index (14) | 6327 |
MDL Number | MFCD00867568 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
Melting point | 94.0 to 98.0 °C |
Properties (reference)
Melting Point | 96 °C |
Solubility in water | Insoluble |
Degree of solubility in water | 43 mg/l |
Solubility (soluble in) | Methanol |
GHS
Pictogram | |
Signal Word | Danger |
Hazard Statements | H302 : Harmful if swallowed. H360 : May damage fertility or the unborn child. H351 : Suspected of causing cancer. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
Related Laws:
RTECS# | MP7746700 |
Transport Information:
H.S.code* | 2941.90-000 |
Application
Mycophenolate mofetil (MMF): An Inhibitor of Inosine Monophosphate Dehydrogenase (IMPDH), Needed for the Growth of T Cells and B Cells
Mycophenolate mofetil (abbrev: MMF) is an ester prodrug of the active immunosuppressant mycophenolic acid (MPA)[M2216] . MPA is a noncompetitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH), an important enzyme in the de novo synthesis of guanosine nucleotides in T and B lymphocytes. MMF is a widely used component of immunosuppressive regimens in organ transplantation. (The product is for research purpose only.)
References
- Mycophenolate mofetil: A review of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in renal transplantation
- Mycophenolate mofetil (a review)
- Mycophenolate mofetil and its mechanisms of action (a review)
- Regulatory T cells induced by 1α,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance
- Mycophenolate mofetil in organ transplantation: focus on metabolism, safety and tolerability (a review)
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