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CAS RN: 88678-31-3 | Product Number: L0301
Liranaftate
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Purity: >98.0%(HPLC)
Synonyms:
- O-(5,6,7,8-Tetrahydronaphthalen-2-yl) (6-Methoxypyridin-2-yl)(methyl)carbamothioate
- (6-Methoxypyridin-2-yl)(methyl)carbamothioic Acid O-(5,6,7,8-Tetrahydronaphthalen-2-yl) Ester
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 50MG |
$199.00
|
3 | 3 | It can be shipped in about 3-4 weeks after ordering | |
| 250MG |
$690.00
|
4 | 2 | It can be shipped in about 3-4 weeks after ordering |
* Please contact our distributors or
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to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | L0301 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__2__0N__2O__2S = 328.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 88678-31-3 |
| Reaxys Registry Number | 12615149 |
| PubChem Substance ID | 354335085 |
| Merck Index (14) | 5515 |
| MDL Number | MFCD00865576 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 8.00 to 9.00 % |
| Melting point | 97.0 to 101.0 °C |
Properties (reference)
| Melting Point | 99 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Chloroform, Acetone, dichloromethane |
| Solubility (slightly sol. in) | Diethyl ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H317 : May cause an allergic skin reaction. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | FD3890000 |
Transport Information:
| H.S.code* | 2933.39-000 |
Application
Liranaftate: A Synthetic Thiocarbamate Antifungal Reagent
Liranaftate (piritetrate or M-732) is a chemical synthetic antifungal reagent, belonging chemically to the thiocarbamates. Although the exact mechanism of action is not entirely known, liranaftate would inhibit sterol biosynthesis at the level of squalene epoxidase which is an important enzyme in the biosynthetic pathway of the fungal membrane. Similar antifungal reagent includes tolnaftate [T3059]. (The product is for research purpose only.)
References
- Inhibitory effect of a new mycotic agent, piritetrate on ergosterol biosynthesis in pathogenic fungi
- In vitro and in vivo activities of piritetrate (M-732), a new antidermatophytic thiocarbamate
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