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CAS RN: 6478-73-5 | Product Number: D5146
5,6-Dichlorobenzimidazole
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Purity: >98.0%(GC)(T)
Synonyms:
Product Documents:
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| 1G |
$119.00
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7 | 1 | Contact Us | |
| 5G |
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|
7 | 14 | Contact Us |
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| Product Number | D5146 |
| Purity / Analysis Method | >98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__7H__4Cl__2N__2 = 187.02 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 6478-73-5 |
| Reaxys Registry Number | 128613 |
| PubChem Substance ID | 354333838 |
| MDL Number | MFCD00211325 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 208.0 to 212.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 210 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2933.99-000 |
Application
5,6-Dichlorobenzimidazole: For the Preparation of 5,6-Dichlorobenzimidazole 1-β- D-Ribofuranoside (DRB) [D4292], and etc.
5,6-Dichlorobenzimidazole is a starting compound for the preparation of 5,6-dichlorobenzimidazole 1-β-D-ribofuranoside (DRB) [D4292], which is a powerful inhibitor of casein kinase-2 (CK-2). 5,6-Dichlorobenzimidazole is also used to synthesize antibacterial benzimidazoles, and etc. For your reference, 5,6-dichlorobenzimidazole hydrochloride is [D4295].
References
- Ribofuranosyl-benzimidazole derivatives as inhibitors of casein kinase-2 and casein kinase-1
- Synthesis of Nucleosides (a review)
- Synthesis and antiparasitic activity of 1H-benzimidazole derivatives
- Synthesis and biological evaluations of novel benzimidazoles as potential antibacterial agents
- Synthesis and in vitro antimicrobial activity of some novel substituted benzimidazole derivatives having potent activity against MRSA
PubMed Literature
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