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CAS RN: 85650-56-2 | Product Number: A3406
Asenapine Maleate
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Purity: >98.0%(HPLC)
Synonyms:
- (3aS,12bS)-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole Maleate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 250MG |
$98.00
|
0 | 0 | It can be shipped in about 1.5 months after ordering |
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to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | A3406 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__1__6ClNO·C__4H__4O__4 = 401.84 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic,Heat Sensitive |
| Packaging and Container | 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 85650-56-2 |
| Reaxys Registry Number | 3647286 |
| PubChem Substance ID | 468590282 |
| MDL Number | MFCD00900588 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 139.0 to 143.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 141 °C |
| Maximum Absorption Wavelength | 270(EtOH) nm |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| H.S.code* | 2934.99-000 |
Application
Asenapine Maleate: A Multi-Receptor Antagonist for 5-HT and Dopamine Receptors
Asenapine maleate is a multi-receptor antagonist and a tetracyclic (atypical) antidepressant agent used for the treatment of schizophrenia and bipolar disorder. The mechanism of action is not completely understood, but neuroscience studies has been suggested that the efficacy of asenapine could be mediated through a combination antagonist activities particularly at 5-HT2A, 5-HT2c, and D2 receptors. (The product is for research purpose only.)
References
- Asenapine Increases Dopamine, Norepinephrine, and Acetylcholine Efflux in the Rat Medial Prefrontal Cortex and Hippocampus
- The preclinical profile of asenapine: clinical relevance for the treatment of schizophrenia and bipolar mania (a review)
- Stress degradation studies and development and validation of RP-HPLC method for the estimation of Asenapine maleate
- Chiral separation of asenapine enantiomers by capillary electrophoresis and characterization of cyclodextrin complexes by NMR spectroscopy, mass spectrometry and molecular modeling
Product Documents (Note: Some products will not have analytical charts available.)
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