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CAS RN: 3544-24-9 | Product Number: A0630
3-Aminobenzamide
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
$100.00
|
7 | 10 | It can be shipped in about 2 weeks after ordering | |
| 25G |
$302.00
|
7 | 4 | It can be shipped in about 2 weeks after ordering |
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to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | A0630 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__7H__8N__2O = 136.15 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
| CAS RN | 3544-24-9 |
| Reaxys Registry Number | 2802373 |
| PubChem Substance ID | 87562201 |
| SDBS (AIST Spectral DB) | 10506 |
| MDL Number | MFCD00007989 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Solubility in Methanol | almost transparency |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 114 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | CU8992000 |
Transport Information:
| H.S.code* | 2924.29-000 |
Application
3-Aminobenzamide: An Inhibitor of Poly (ADP-Ribose) Polymerase (PARP) Enzymes
Genomic instability is a hallmark of cancer and is often the result of altered DNA repair capabilities in tumor cells. Poly (ADP-ribose) polymerases (PARPs) are enzymes responsible for DNA damage detection and repair factor recruitment. PARP inhibitors are able to interact with the binding site for the PARP cofactor NAD+ and trap PARP on DNA, and induce cell death through replication stress-induced mitotic catastrophe. It has been reported that 3-aminobenzamide is a PARP inhibitor and is used for cancer research. (The product is for research use only.)
References
- Possible Involvement of Poly(ADP-Ribosyl) Polymerase in Triggering Stress-Induced Apoptosis
- Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly(ADP-ribose) synthetase
- Current Overview on the Usage of Poly(ADP-ribose)polymerase ( ARP) Inhibitors PARP in Treating Cancer (a review)
PubMed Literature
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