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CAS RN: 52549-17-4 | Product Number: P2778
Pranoprofen
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Purity: >98.0%(GC)(T)
Synonyms:
- 2-(5H-Chromeno[2,3-b]pyridin-7-yl)propanoic Acid
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 1G |
$204.00
|
Contact Us | Contact Us | 2 |
|
| 5G |
$610.00
|
Contact Us | Contact Us | 9 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | P2778 |
| Purity / Analysis Method | >98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__5H__1__3NO__3 = 255.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 52549-17-4 |
| Reaxys Registry Number | 889798 |
| PubChem Substance ID | 468592719 |
| MDL Number | MFCD00866111 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 184.0 to 188.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 186 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Dimethylformamide |
| Solubility (slightly sol. in) | Methanol |
| Solubility (insoluble in) | Diethyl ether |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | DJ3100950 |
Transport Information:
| UN Number (DOT-AIR) | UN2811 |
| Class (DOT-AIR) | 6.1 |
| Packing Group (TCI-A) | III |
| HS Number | 2934.99.4400 |
Application
Pranoprofen: a non-selective cyclooxygenase (COX) inhibitor
Pranoprofen, a non-steroidal anti-inflammatory agents (NSAIDs), is a non-selective cyclooxygenase-1 and -2 (COX-1 and -2) inhibitor. COXs are responsible for the formation of prostaglandins which play a key role in the generation of the inflammatory response. The inhibition of prostaglandin synthesis are effective in suppressing inflammation. In clinical, pranoprofen is used as an ophthalmic medicine to treat inflammation, keratitis, conjunctivitis and blepharitis after eye surgery. (The product is for research purpose only.)
References
- Topical pranoprofen 0.1% is as effective anti-inflammatory and analgesic agent as diclofenac sodium 0.1% after strabismus surgery
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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