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CAS RN: 58-33-3 | Product Number: P2029
Promethazine Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 10-[2-(Dimethylamino)propyl]phenothiazine Hydrochloride
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 25G |
$59.00
|
5 | 1 | 11 |
|
| 100G |
$182.00
|
7 | 3 | 1 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | P2029 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__2__0N__2S·HCl = 320.88 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive |
| CAS RN | 58-33-3 |
| Related CAS RN | 60-87-7 |
| Reaxys Registry Number | 4166397 |
| PubChem Substance ID | 160871508 |
| Merck Index (14) | 7786 |
| MDL Number | MFCD00012652 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 226 °C |
| Maximum Absorption Wavelength | 297 nm (H__2O) |
| Solubility (insoluble in) | Ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H411 : Toxic to aquatic life with long lasting effects. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P391 : Collect spillage. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | SO8225000 |
Transport Information:
| UN Number (DOT-AIR) | UN3077 |
| Class (DOT-AIR) | 9 |
| Packing Group (TCI-A) | III |
| HS Number | 2934.99.4400 |
Application
Efflux pump research / Biofilm research
References
- Antifungal activity of promethazine and chlorpromazine against planktonic cells and biofilms of Cryptococcus neoformans/Cryptococcus gattii complex species
- The Role of Efflux Pumps and Environmental pH in Bacterial Multidrug Resistance
- Synergistic Effects of Efflux Pump Modulators on the Azole Antifungal Susceptibility of Microsporum canis
- In vitro effects of promethazine on cell morphology and structure and mitochondrial activity of azole-resistant Candida tropicalis
Application
Formulation and its Related Studies of Promethazine Hydrochloride
References
- Formulation of sustained-release promethazine hydrochloride tablets using hydroxypropyl methyl cellulose matrixes
- Adsorption of promethazine hydrochloride with KSF montmorillonite
- Release of cationic drugs from loaded clay minerals
- I. Fejer, M. Kata, I. Eros, O. Berkesi, I. Dekany, Colloid. Polym. Sci. 2001, 279, 1177.
- Colorimetric determination of captopril in dosage forms
- S. M. El-Ashry, F. A. Ibrahim, Anal. Lett. 1992, 25, 1657.
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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