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CAS RN: 113-98-4 | Product Number: P1772

Penicillin G Potassium Salt


Purity: >98.0%(HPLC)(N)
Synonyms:
  • Benzylpenicillin Potassium Salt
Product Documents:
25G
$57.00
2   1   ≥100 

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Supplemental Product Information:

This product has not been tested for potency and is guaranteed for chemical purity.

Product Number P1772
Purity / Analysis Method >98.0%(HPLC)(N)
Molecular Formula / Molecular Weight C__1__6H__1__7KN__2O__4S = 372.48 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Hygroscopic
CAS RN 113-98-4
Related CAS RN 61-33-6
Reaxys Registry Number 3832841
PubChem Substance ID 87560525
Merck Index (14) 7094
MDL Number

MFCD00036193

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Specific rotation [a]20/D +270.0 to +300.0 deg(C=1, H2O)
Properties (reference)
Melting Point 217 °C(dec.)
Specific Rotation 294° (C=1,H2O)
Solubility in water Soluble
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H317 : May cause an allergic skin reaction.
H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P285 : In case of inadequate ventilation wear respiratory protection.
P280 : Wear protective gloves.
P272 : Contaminated work clothing must not be allowed out of the workplace.
P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor.
P304 + P341 : IF INHALED: If breathing is difficult, remove person to fresh air and keep comfortable for breathing.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention.
P363 : Wash contaminated clothing before reuse.
Related Laws:
RTECS# XH9700000
Transport Information:
HS Number 2941.10.2000
Application
Penicillin G: The First Antibiotic belongs to Penicillins

Penicillin is the first antibiotic isolated from the mold Penicillium noctum, specifically it is known as penicillin G (other name: benzylpenicillin) and belongs to a class of similar antibiotics called penicillins. Nowadays penicillin G is produced by Penicillium chrysogenum fermentation. Penicillin G has activity against Gram-positive bacteria, but less activity against Gram-negative bacteria. It acts as a competitive inhibitor of the enzyme transpeptidase, which is needed by bacteria to make their cell walls. Meanwhile, β-lactamases (also called penicillinases) are enzymes produced by bacteria that deactivate penicillin G by destroying the β-lactam ring via hydrolysis. In rare cases, an allergy to penicillin G can cause an anaphylactic reaction, which can be deadly. Currently, the enzymatic hydrolysis of penicillin G gives 6-aminopenicillanic acid (6-APA) [A0800], which is a basic raw material for the industrial production of semisynthetic β-lactamase-resistant and broad spectrum penicillins such as amoxycillin [A2099] and ampicillin [A2092].

References


PubMed Literature


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