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CAS RN: 132866-11-6 | Product Number: L0282
Lercanidipine Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 200MG |
$16.00
|
1 | 1 | 8 |
|
| 1G |
$44.00
|
3 | 1 | 11 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | L0282 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__3__6H__4__1N__3O__6·HCl = 648.20 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Light Sensitive,Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 132866-11-6 |
| Related CAS RN | 100427-26-7 |
| Reaxys Registry Number | 7406263 |
| PubChem Substance ID | 253660808 |
| Merck Index (14) | 5446 |
| MDL Number | MFCD07773089 |
Specifications
| Appearance | Light orange to Yellow to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 195 °C(dec.) |
| Solubility (soluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
Transport Information:
| HS Number | 2933.39.6191 |
Application
Paraptosis research
Reference
- Lercanidipine Synergistically Enhances Bortezomib Cytotoxicity in Cancer Cells via Enhanced Endoplasmic Reticulum Stress and Mitochondrial Ca2+ Overload
- Pharmacological in vitro studies of the new 1,4-dihydropyridine calcium antagonist lercanidipine
- L. Guarneri, P. Angelico, M. Ibba, E. Poggesi, C, Taddei, A. Leonardi, R. Testa, Arzneim.-Forsch. 1996, 46, 15.
- Lercanidipine (Rec 15/2375): a novel 1,4-dihydropyridine calcium antagonist for hypertension (a review)
- Development and evaluation of buccoadhesive controlled release tablets of lercanidipine
- Oral self emulsifying powder of lercanidipine hydrochloride: Formulation and evaluation
- Determination of lercanidipine hydrochloride and its impurities in tablets
Application
Lercanidipine Hydrochloride: A Vascular-Selective Dihydropyridine Calcium Channel Antagonist
Lercanidipine hydrochloride is a long-lasting and vascular-selective dihydropyridine calcium channel antagonist that causes vasodilatation by blocking the influx of calcium ions through L-type calcium channels in cell membranes. Recently, formulations of lercanidipine hydrochloride have been studied to improve its bioavailability. (The product is for research purpose only.)
References
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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