Make sure to sign up for an account today for exclusive coupons and free shipping on orders over $75!
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 147591-46-6 | Product Number: I1108
ID 8
×
![]()
×
Purity: >98.0%(GC)
Synonyms:
- 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 10MG |
$111.00
|
Contact Us | Contact Us | 14 |
|
| 50MG |
$383.00
|
Contact Us | Contact Us | 20 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | I1108 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__4N__2O__4 = 298.30 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Condition to Avoid | Light Sensitive,Heat Sensitive |
| CAS RN | 147591-46-6 |
| Reaxys Registry Number | 5825601 |
| PubChem Substance ID | 468592099 |
| MDL Number | MFCD00593367 |
Specifications
| Appearance | Light yellow to Amber to Dark green powder to crystal |
| Purity(GC) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 266 °C(dec.) |
GHS
Related Laws:
Transport Information:
| HS Number | 2933.99.7900 |
Application
Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase (DYRK) Inhibitor
ID 8 (1) was reported as an indole derivative that can sustain embryonic stem cell self-renewal in long-term culture.1)1 inhibits dual-specificity tyrosine phosphorylation-regulated kinase (DYRK).2) 1 supports Wnt-induced human embryonic stem cell proliferation and survival without fibroblast growth factor (FGF) and tumor growth factor-β (TGF-β) supplementation.2)
References
- 1) Indole derivatives sustain embryonic stem cell self-renewal in long-term culture
- 2) Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion
Articles/Brochures
TCIMAIL
[TCIMAIL No.188] Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase (DYRK) InhibitorProduct Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.