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CAS RN: 873857-62-6 | Product Number: F1216
Fidaxomicin
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Purity: >98.0%(HPLC)
Synonyms:
- Tiacumicin B
- Lipiarmycin A3
- Clostomicin B1
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 25MG |
$104.00
|
1 | Contact Us | 14 |
|
| 100MG |
$287.00
|
2 | Contact Us | 28 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | F1216 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__5__2H__7__4Cl__2O__1__8 = 1,058.05 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 873857-62-6 |
| Reaxys Registry Number | 12687773 |
| PubChem Substance ID | 468591852 |
| MDL Number | MFCD27976367 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
Properties (reference)
| Melting Point | 161 °C |
| Specific Rotation | -6.9° (C=2,MeOH) |
GHS
Related Laws:
Transport Information:
| HS Number | 2941.90.3000 |
Application
Fidaxomicin: A Narrow-Spectrum Macrolide Antibiotic Active against Clostridia
Fidaxomicin (OPT-80) is a narrow-spectrum macrolide antibiotic obtained from the Actinomycete Dactylosporangium aurantiacum. Fidaxomicin is active primarily against species of clostridia, including Clostridium difficile (or Clostridioides difficile) that is a major cause of hospital-acquired diarrhea and mortality in individuals. Fidaxomicin has demonstrated potent in vitro bactericidal activity, inhibiting RNA synthesis by RNA polymerases, with limited or no activity against normal fecal flora. In addition, it is minimally absorbed from the intestinal tract. (The product is for research purpose only.)
文献
- OPT-80 Eliminates Clostridium difficile and Is Sparing of Bacteroides Species during Treatment of C. difficile Infection
- A new macrocyclic antibiotic, fidaxomicin (OPT-80), causes less alteration to the bowel microbiota of Clostridium difficile-infected patients than does vancomycin
- Antimicrobial Activities of Fidaxomicin (a review)
Articles/Brochures
TCIMAIL
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Safety Data Sheet (SDS)
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Specifications
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