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CAS RN: 57-87-4 | Product Number: E0018
Ergosterol
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Purity: >95.0%(GC)
Synonyms:
- Provitamin D2
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 5G |
$72.00
|
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|
| 25G |
$207.00
|
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|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | E0018 |
Purity / Analysis Method 
|
>95.0%(GC) |
| Molecular Formula / Molecular Weight | C__2__8H__4__4O = 396.66 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Hygroscopic,Heat Sensitive |
| CAS RN | 57-87-4 |
| Reaxys Registry Number | 2338604 |
| PubChem Substance ID | 87569337 |
| SDBS (AIST Spectral DB) | 2246 |
| Merck Index (14) | 3659 |
| MDL Number | MFCD00003623 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 95.0 % |
| Melting point | 156.0 to 162.0 °C |
| Specific rotation [a]20/D | -100 to -125 deg(C=1, THF)(calcd.on anh.substance) |
| Absorbance | min. 0.500(20 mg/L, 269.0 to 273.0 nm) |
| Absorbance2 | min. 0.530(20 mg/L, 280.0 to 284.0 nm) |
| Water | max. 7.0 % |
Properties (reference)
| Melting Point | 159 °C |
| Boiling Point | 250 °C/0.01 mmHg |
| Specific Rotation | -113° (C=1,THF) |
GHS
Related Laws:
Transport Information:
| HS Number | 2936.90.0110 |
Application
Ergosterol: A Sterol Found in Cell Membranes of Fungi
Ergosterol is a sterol found in cell membranes of fungi which use principally it instead of cholesterol [C0318] on humans and other mammals. So many antifungal agents target ergosterol as a way to disrupt the fungal plasma membrane. Ergosterol is also called provitamin D2 because exposure it to ultraviolet (UV) light causes a chemical reaction that produces vitamin D2 (calciferol or ergocalciferol) [C0005].
References
- The biosynthesis of ergosterol (a review)
- Ergosterol content in various fungal species and biocontaminated building materials
- The biology and chemistry of antifungal agents: A review
- A new mechanistic scenario for the photochemical transformation of ergosterol: an MC-SCF and MM-VB [molecular mechanics-VB] study
- Sterol and vitamin D2 concentrations in cultivated and wild grown mushrooms: Effects of UV irradiation
PubMed Literature
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