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CAS RN: 477-43-0 | Product Number: D5366
Dehydrocostus Lactone
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Purity: >98.0%(GC)
Synonyms:
- (3aS,6aR,9aR,9bS)-3,6,9-Trimethylenedecahydroazuleno[4,5-b]furan-2(9bH)-one
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 10MG |
$81.00
|
1 | 1 | 29 |
|
| 50MG |
$250.00
|
1 | Contact Us | 23 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
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| Product Number | D5366 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__8O__2 = 230.31 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Packaging and Container | 10MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 477-43-0 |
| Reaxys Registry Number | 4733740 |
| PubChem Substance ID | 354335524 |
| MDL Number | MFCD00210277 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 57.0 to 61.0 °C |
Properties (reference)
| Melting Point | 59 °C |
| Specific Rotation | -11° (C=1,CHCl3) |
| Maximum Absorption Wavelength | 206(MeOH) nm |
GHS
Related Laws:
Transport Information:
| HS Number | 2914.79.4000 |
Application
Dehydrocostus Lactone: A Natural Sesquiterpene with Various Bioactivities
Dehydrocostus lactone is a natural sesquiterpene first isolated from Saussurea costus root, which is used in traditional medicine.1) Pharmacological experiments have demonstrated the ability of dehydrocostus lactone to exhibit anti-fungal, anti-inflammatory, anti-ulcer, anti-cancer and hepatoprotective activities.2-5) (The product is for research purpose only.)
References
- 1)Saussurea costus: Botanical, chemical and pharmacological review of an ayurvedic medicinal plant (a review)
- 2)A sesquiterpene, dehydrocostus lactone, inhibits the expression of inducible nitric oxide synthase and TNF-α in LPS-activated macrophages
- 3)Fungicidal activity of natural and synthetic sesquiterpene lactone analogs
- 4)Inhibition of inflammatory and proliferative responses of human keratinocytes exposed to the sesquiterpene lactones dehydrocostuslactone and costunolide (a review)
- 5)Potential anti-cancer activities and mechanisms of costunolide and dehydrocostuslactone (a review)
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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