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CAS RN: 478-43-3 | Product Number: D3986
4,5-Dihydroxyanthraquinone-2-carboxylic Acid
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Purity: >95.0%(T)(HPLC)
Synonyms:
- Rhein
- Cassic Acid
- Rhubarb Yellow
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 200MG |
$44.00
|
Contact Us | Contact Us | 18 |
|
| 1G |
$130.00
|
1 | Contact Us | 11 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | D3986 |
| Purity / Analysis Method | >95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__8O__6 = 284.22 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 478-43-3 |
| Reaxys Registry Number | 2222155 |
| PubChem Substance ID | 125307728 |
| Merck Index (14) | 8176 |
| MDL Number | MFCD00009618 |
Specifications
| Appearance | Light yellow to Brown powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Neutralization titration) | min. 95.0 % |
Properties (reference)
| Melting Point | 321 °C |
| Maximum Absorption Wavelength | 432(MeOH) nm |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse. |
Related Laws:
| RTECS# | CA9516000 |
Transport Information:
| HS Number | 2918.99.4700 |
Application
Bone research
References
- Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling
- Diacerhein and rhein reduce the ICE-induced IL-1β and IL-18 activation in human osteoarthritic cartilage
Application
Rhein; A Bioactive Anthraquinone Isolated from Rheum palmatum L.
Rhein is an anthraquinone, isolated from several traditional Chinese medicines, including Rheum palmatum L. It has been reported that rhein exerts various pharmacological activities, such as anti-inflammatory, antitumor, antioxidant, antifibrosis, hepatoprotective, and nephroprotective activities. (The product is for research purpose only.)
References
- Anti-cancer properties of anthraquinones from Rhubarb (a review)
- A comprehensive and system review for the pharmacological mechanism of action of rhein, an active anthraquinone ingredient (a review)
- Research Progress on the Antitumor Effects of Rhein: Literature Review
- Pharmacokinetic analysis of rhein in Rheum undulatum L
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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