Make sure to sign up for an account today for exclusive coupons and free shipping on orders over $75!
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 54856-23-4 | Product Number: B1424
Betahistine Methanesulfonate
×
![]()
×
Purity: >99.0%(T)(HPLC)
Synonyms:
- Betahistine Mesylate
- 2-[2-(Methylamino)ethyl]pyridine Methanesulfonate
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 25G |
$70.00
|
2 | 1 | ≥40 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | B1424 |
| Purity / Analysis Method | >99.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__8H__1__2N__2·2CH__4O__3S = 328.40 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
| CAS RN | 54856-23-4 |
| Related CAS RN | 5638-76-6 |
| Reaxys Registry Number | 4043104 |
| PubChem Substance ID | 87564344 |
| MDL Number | MFCD00143688 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 99.0 area% |
| Purity(Neutralization titration) | min. 99.0 % |
| Melting point | 112.0 to 115.0 °C |
| Solubility in Water | almost transparency |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 112 °C |
GHS
Related Laws:
| RTECS# | UT2970200 |
Transport Information:
| HS Number | 2933.39.9200 |
Application
Betahistine Methanesulfonate: A Histamine H1 Receptor Agonist/H3 Antagonist
Betahistine methanesulfonate is a structural analog of histamine [H0146, dihydrochloride] that acts both as a partial histamine H1-receptor agonist and histamine H3-receptor antagonist in neuronal tissue. Betahistine increases histamine turnover and release by blocking presynaptic H3-receptors and inducing H3-receptor downregulation.1-3) Reportedly, betahistine increases in vestibular blood flow, and is used as an antivertigo agent in clinical.2,3) Recently, it has been reported that betahistine induced the recall of forgotten memories in mice.4) (The product is for research purpose only.)
References
- 1) Actions of betahistine at histamine receptors in the brain
- 2) Betahistine increases vestibular blood flow
- 3) Histamine and betahistine in the treatment of vertigo: Elucidation of mechanisms of action (a review)
- 4) Central Histamine Boosts Perirhinal Cortex Activity and Restores Forgotten Object Memories
- 5) LC-MS-MS analysis of 2-pyridylacetic acid, a major metabolite of betahistine: application to a pharmacokinetic study in healthy volunteers
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.