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CAS RN: | Product Number: A2701

Anti-GalNAc-GD1a Monoclonal Antibody (2A3D2)


Purity:
Synonyms:
Product Documents:
1VIAL
$715.00
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Supplemental Product Information:

Product Information

Volume/Quantity : 0.1 mg/vial
Product Form : Purified mouse monoclonal antibody/IgM, κ-chain
Buffer : Phosphate buffered-saline (PBS)
Preparation : The antibody is purified from ascites fluid
Preservative : 0.05% Sodium azide
Stabilizer : None
Immunogen : Salmonella minnesota strain R595 coated with ganglioside mixture from human hepatocellular carcinoma cells, PLC/PRF/5
Specificity : Ganglioside GalNAc-GD1a. This antibody recognizes terminal GalNAcβ1→4(NeuAcα2→3)Galβ-R structure, and reacts to GM2, GalNAc-sialyl-nLc4, and Cad-active glycoproteins.
Clone Name : 2A3D2

Application

ELISA, Immunohistochemistry, Immunoprecipitation, Western blot, TLC-immunostaining.


Storage

Store at −20 °C to −80 °C (Preferably at −80 °C). Storage at 4 °C is not recommended. Avoid repeated freezing and thawing.


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G0453 Goat Anti-Mouse IgM FITC Conjugate

Product Number A2701
Physical State (20 deg.C) Liquid
Storage Temperature Frozen (-80°C)
Condition to Avoid Heat Sensitive
Specifications
Appearance Colorless to Almost colorless clear liquid
Titer(ELISA) to pass test
Properties (reference)
GHS
Related Laws:
Transport Information:
HS Number 3504.00.5000
Application
Anti-GalNAc-GD1a Monoclonal Antibody

References

  • Gangliosides and sialoglycoproteins carrying a rare blood group antigen determinant, Cad, associated with human cancers as detected by specific monoclonal antibodies
    • N. Hiraiwa, K. Tsuyuoka, Y.-T. Li, M. Tanaka, T. Seno, Y. Okubo, Y. Fukuda, H. Imura, R. Kannagi, Cancer Res. 1990, 50, 5497.
  • Northern hybridization analysis of VH gene expression in murine monoclonal antibodies directed to cancer-associated ganglioside antigens having various sialic acid linkages
    • K. Zenita, K. Hirashima, K. Shigeta, N. Hiraiwa, A. Takada, K. Hashimoto, E. Fujimoto, K. Yago, R. Kannagi, J. Immunol. 1990, 144, 4442.
  • Localization of UDP-GalNAc:NeuAcα-2,3Gal-Rβ-1,4(GalNAc to Gal)N- acetylgalactosaminyltransferase in human stomach. Enzymatic synthesis of a fundic gland-specific ganglioside and GM2
    • T. Dohi, N. Hanai, K. Yamaguchi, M. Oshima, J. Biol. Chem. 1991, 266, 24038.
  • Induction of the fundic mucosa-specific glycolipid with dimethylformamide in gastric-cancer cell lines
  • A guide to monoclonal antibodies directed to glycotopes
    • R. Kannagi, S. Hakomori, Adv. Exp. Med. Biol. 2001, 491, 587.
  • Red blood cell antigens responsible for inherited types of polyagglutination
    • E. Lisowska, M. Duk, Adv. Exp. Med. Biol. 2001, 491, 141.


Articles/Brochures

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