Cyclophosphamide Monohydrate

References

• Uroprotective effect of pentoxifylline in cyclophosphamide-induced hemorrhagic cystitis in rats
  • O. M. Abo-Salem, J. Biochem Mol. Toxicol. 2013, 27, 343.
• Relevance of the cyclophosphamide-induced cystitis model for pharmacological studies targeting inflammation and pain of the bladder
  • C. Auge, G. Chene, M. Dubourdeau, D. Desoubzdanne, B. Corman, S. Palea, P. Lluel, N. Vergnolle, A. M. Coelho, Eur. J. Pharmacol. 2013, 707, 32.
• Effect of intrathecal administration of E-series prostaglandin 1 receptor antagonist in a cyclophosphamide-induced cystitis rat model
  • N, Wada, S. Matsumoto, M. Kita, M. Watanabe, K. Hashizume, H. Kakizaki, Int. J. Urol. 2013, 20, 235.
• Effect of silymarin on bladder overactivity in cyclophosphamide-induced cystitis rat model
  • N. Eser, C. Gocmen, S. Erdo?an, H. S. Buyuknacar, E. K. Kumcu, A. Ac?kal?n, S. Onder, Phytomedicine 2012, 19, 840.

References

• A rabbit used as a model for testing hematopoietic tissue transplants
  • S. Kosi?ski, H. Matej, Arch. Immunol. Ther. Exp. (Warsz) 1978, 26, 1021.
• Immunomodulatory effects of moxifloxacin in comparison to ciprofloxacin and G-CSF in a murine model of cyclophosphamide-induced leukopenia
  • I Shalit, Y. Kletter, D. Halperin, D. Waldman, E. Vasserman, A. Nagler, I. Fabian, Eur. J. Haematol. 2001, 66, 287.

References

• Cyclophosphamide cystitis--identification of acrolein as the causative agent
  • P. J. Cox,Biochem Pharmacol. 1979, 28, 2045.
• Cyclophosphamide cystitis in rats: involvement of capsaicin-sensitive primary afferents
  • C. A. Maggi, A. Lecci, P. Santicioli, E. Del Bianco, S. Giuliani, J. Auton. Nerv. Syst. 1992, 38, 201.
• Increased excitability of afferent neurons innervating rat urinary bladder after chronic bladder inflammation
  • N. Yoshimura, W. C. de Groat, J. Neurosci. 1999, 19, 4644.
• Cyclophosphamide cystitis in mice: behavioural characterisation and correlation with bladder inflammation
  • T. Olivar, J. M. Laird, Eur. J. Pain. 1999, 3, 141.
• Cyclophosphamide-induced cystitis in freely-moving conscious rats: behavioral approach to a new model of visceral pain
  • M. Boucher, M. Meen, J. P. Codron, F. Coudore, J. L. Kemeny, A. Eschalier, J. Urol. 2000, 164, 203.
• Comparison of voiding function and nociceptive behavior in two rat models of cystitis induced by cyclophosphamide or acetone
  • C. Saitoh, H. Yokoyama, M. B. Chancellor, W. C. de Groat, N. Yoshimura, Neurourol. Urodyn. 2010, 29, 501.

References

• The antiemetic effect of a novel tropisetron patch in anticancer agents-induced kaolin pica model using rats
  • S. W. Jeong, J. W. Cho, J. S. Hwang, J. D. Song, S. Shin, J. Y. Jang, S. Y. Hwang, O. Kim, J. C. Kim, Y. B. Kim, J. K. Kang, Environ. Toxicol. Pharmacol. 2005, 20, 167.
• The anti-cancer drug-induced pica in rats is related to their clinical emetogenic potential
  • K. Yamamoto, M. Nakai, K. Nohara, A. Yamatodani, Eur. J. Pharmacol. 2007, 554, 34.

References

• An overview of cyclophosphamide and ifosfamide pharmacology
  • R. A. Fleming, Pharmacotherapy 1997, 17, 146S.
• Cyclophosphamide: Review of its mutagenicity for an assessment of potential germ cell risks
  • D. Anderson, J. B. Bishop, R. C. Garner, P. Ostrosky-Wegman, P. B. Selby, Mutat. Res. 1995, 330, 115.
• The chemistry of the metabolites of cyclophosphamide
  • S. M. Ludeman, Curr. Pharm. Des. 1999, 5, 627.
• Mechanisms of resistance to the toxicity of cyclophosphamide
  • M. P. Gamcsik, M. E. Dolan, B. S. Andersson, D. Murray, Curr. Pharm. Des. 1999, 5, 587.

Reference

• H. Arnold, F. Bourseaux, Angew. Chem. 1958, 70, 539.

Reference

• Optical resolution studies of cyclophosphamide
  • T. Kawashima, R. D. Kroshefsky, R. A. Kok, J. G. Verkade, J. Org. Chem. 1978, 43, 1111.