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CAS RN: 482-27-9 | 제품번호: I0861
Isopimpinellin
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| 포장단위 | 가격 | 당일출고 | 2-3일 이내 출고 |
|---|---|---|---|
| 10MG |
₩434,800
|
10 | 문의 |
•본 제품의 재고는 일본 본사의 재고입니다. 주문시, 5일안에 실험실까지 도착됩니다.
•본건의 원가격은 한국 대리점의 예상 판매가격입니다.자세한 정보가 필요하시면 연락해 주십시오.(SEJIN CI Co., Ltd. (한국총대리점) 전화 : 02-2655-2480 이메일 : sales@sejinci.co.kr)
•보관 조건은 예고없이 변경 될 수 있습니다. 제품 보관 조건의 최신 자료는 홈페이지에 기재되어 있으니 양해 부탁드립니다.
•본건의 원가격은 한국 대리점의 예상 판매가격입니다.자세한 정보가 필요하시면 연락해 주십시오.(SEJIN CI Co., Ltd. (한국총대리점) 전화 : 02-2655-2480 이메일 : sales@sejinci.co.kr)
•보관 조건은 예고없이 변경 될 수 있습니다. 제품 보관 조건의 최신 자료는 홈페이지에 기재되어 있으니 양해 부탁드립니다.
| 제품번호 | I0861 |
| Purity/Analysis Method | >98.0%(GC) |
| M.F. / M.W. | C__1__3H__1__0O__5 = 246.22 |
| 물리적 상태 (20 ℃) | Solid |
| 보관 조건 | Room Temperature (Recommended in a cool and dark place, <15°C) |
| 용기 | 10MG-Glass Bottle with Plastic Insert (이미지 보기) |
| CAS RN | 482-27-9 |
| Reaxys-RN | 262337 |
| PubChem Substance ID | 172089036 |
| MDL 번호 | MFCD00017407 |
규격표
| Appearance | Light yellow to Yellow to Green powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 148.0 to 152.0 °C |
| NMR | confirm to structure |
물성치(참고치)
| mp | 150 °C |
| Maximum Wavelength | 268(MeOH) nm |
GHS
법규 정보
| RTECS # | LV1049200 |
운송 정보
| HS 번호* | 2932.99-000 |
Application
A Bioactive Component in Apiaceae (Umbelliferae)
Isopimpinellin, a kind of furanocoumarin, is found in Apiaceae (Umbelliferae) such as celery and parsley, and Citrus such as lime and grapefruit.1) It has been known that furanocoumarins as typified by bergamottin induce photodermatosis, which is produced in plants as a defense against herbivorous animals.2) However, isopimpinellin does not have phototoxicity,3) but has an antifungal effect, an insecticidal effect and an antifeeding effect.4) In addition, Cnidii Monnieri Fructus, dried fruits of Cnidium monnieri CUSSON (Apiaceae), contains isopimpinellin, and is used as a crude drug in traditional Chinese medicine. The evidence of an antipruritic effect has been revealed.5) It has been also reported that isopimpinellin regulates cytochromes P450 (hepatic detoxicating enzymes) and inhibits tumorigenesis induced by the metabolites of polycyclic aromatic hydrocarbons (PAHs).6) (The product is for research purpose only.)
References
- 1) The natural coumarins: occurrence, chemistry and biochemistry
- 2) Furanocoumarin induction in wild parsnip: Evidence for an induced defense against herbivores
- 3) a) Furocoumarins of Heracleum Laciniatum: isolation, phototoxicity, absorption and action spectra studies
- b) Isopimpinellin is not phototoxic in a chick skin assay
- 4) a) Antifungal activity of coumarins
- b) Insecticidal effect of phthalides and furanocoumarins from Angelica acutiloba against Drosophila
melanogaster - c) Osthol and isopimpinellin from Fructus cnidii for the control of Dactylogyrus intermedius in Carassius
auratus - d) Phloroglucinol-type furocoumarins, a group of potent naturally-occurring insect antifeedants
- 5) a) Inhibition of itch-scratch response by fruits of Cnidium monnieri in mice
- b) Antipruritic effect of Cnidii Monnieri Fructus (fruits of Cnidium monnieri Cusson)
- 6) a) Inhibition and inactivation of murine hepatic ethoxy- and pentoxyresorufin O-dealkylase by naturally
occurring coumarins - b) Oral administration of the citrus coumarin, isopimpinellin, blocks DNA adduct formation and skin tumor
initiation by 7,12-dimethylbenz[α]anthracene in SENCAR mice - c) Effects of naturally occurring coumarins on hepatic drug metabolizing enzymes in mice
PubMed Literature
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