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CAS RN: 99011-02-6 | ์ œํ’ˆ๋ฒˆํ˜ธ: I0747

Imiquimod

Chemical Structure of Imiquimod

์ˆœ๋„/๋ถ„์„ ๋ฐฉ๋ฒ•: >98.0%(T)(HPLC)
๋™์˜์–ด์˜:
  • 1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
  • 4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline
์ œํ’ˆ๋ฌธ์„œ:
100MG
โ‚ฉ154,100
5   0   ๋ฌธ์˜
1G
โ‚ฉ795,600
≥60  9   ๋ฌธ์˜
โ€ข๋ณธ ์ œํ’ˆ์˜ ์žฌ๊ณ ๋Š” ์ผ๋ณธ ๋ณธ์‚ฌ์˜ ์žฌ๊ณ ์ž…๋‹ˆ๋‹ค. ์ฃผ๋ฌธ์‹œ, 5์ผ์•ˆ์— ์‹คํ—˜์‹ค๊นŒ์ง€ ๋„์ฐฉ๋ฉ๋‹ˆ๋‹ค.
โ€ข๋ณธ๊ฑด์˜ ์›๊ฐ€๊ฒฉ์€ ํ•œ๊ตญ ๋Œ€๋ฆฌ์ ์˜ ์˜ˆ์ƒ ํŒ๋งค๊ฐ€๊ฒฉ์ž…๋‹ˆ๋‹ค.์ž์„ธํ•œ ์ •๋ณด๊ฐ€ ํ•„์š”ํ•˜์‹œ๋ฉด ์—ฐ๋ฝํ•ด ์ฃผ์‹ญ์‹œ์˜ค.( SEJIN CI Co., Ltd. (ํ•œ๊ตญ์ด๋Œ€๋ฆฌ์ ) ์ „ํ™” : 02-2655-2480 ์ด๋ฉ”์ผ :  sales@sejinci.co.kr)
โ€ข๋ณด๊ด€ ์กฐ๊ฑด์€ ์˜ˆ๊ณ ์—†์ด ๋ณ€๊ฒฝ ๋  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ์ œํ’ˆ ๋ณด๊ด€ ์กฐ๊ฑด์˜ ์ตœ์‹  ์ž๋ฃŒ๋Š” ํ™ˆํŽ˜์ด์ง€์— ๊ธฐ์žฌ๋˜์–ด ์žˆ์œผ๋‹ˆ ์–‘ํ•ด ๋ถ€ํƒ๋“œ๋ฆฝ๋‹ˆ๋‹ค.

์ œํ’ˆ๋ณด์ถฉ์ •๋ณด:

This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.

์ œํ’ˆ๋ฒˆํ˜ธ I0747
Purity/Analysis Method >98.0%(T)(HPLC)
M.F. / M.W. C__1__4H__1__6N__4 = 240.31 
๋ฌผ๋ฆฌ์  ์ƒํƒœ (20 โ„ƒ) Solid
๋ณด๊ด€ ์กฐ๊ฑด Room Temperature (Recommended in a cool and dark place, <15ยฐC)
์šฉ๊ธฐ 100MG-Glass Bottle with Plastic Insert (์ด๋ฏธ์ง€ ๋ณด๊ธฐ),  1G-Glass Bottle with Plastic Insert (์ด๋ฏธ์ง€ ๋ณด๊ธฐ)
CAS RN 99011-02-6
Reaxys-RN 7710060
PubChem Substance ID 87561300
Merck Index (14) 4922
MDL ๋ฒˆํ˜ธ

MFCD00866946

๊ทœ๊ฒฉํ‘œ
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
๋ฌผ์„ฑ์น˜(์ฐธ๊ณ ์น˜)
mp 294 ยฐC
Maximum Wavelength 245 nm (H__2O/MeOH)
GHS
ํ”ฝํ† ๊ทธ๋žจ Pictogram
์‹ ํ˜ธ ์›Œ๋“œ Danger
์œ„ํ—˜๋ฌผ ๋ฐ ์œ ํ•ด ๋“ฑ๋ก H301 : Toxic if swallowed.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
์ฃผ์˜ ์‚ฌํ•ญ P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
๋ฒ•๊ทœ ์ •๋ณด
RTECS # NJ5903450
์šด์†ก ์ •๋ณด
UN ๋ฒˆํ˜ธ UN2811
๋“ฑ๊ธ‰ 6.1
ํฌ์žฅ ๊ทธ๋ฃน III
HS ๋ฒˆํ˜ธ* 2933.99-000
*์ด HS ๋ฒˆํ˜ธ ๋Š” TCI(์ผ๋ณธ)์—์„œ ์ œํ’ˆ์„ ์ˆ˜์ถœํ•  ๋•Œ๋งŒ ์‚ฌ์šฉ๋ฉ๋‹ˆ๋‹ค
Application
Imiquimod: A Toll-Like Receptor (TLR) 7 Agonist and a Potent Immune Activator

Imiquimod is reported as a Toll-like receptor (TLR) 7 agonist and a potent immune activator. Imiquimod activates innate immune cells to produce interferon-α (IFN-α) and other cytokines both in vitro and in vivo. This immune-based mechanism provides activity against a number of viruses. In addition, it is also used for a reagent for inflammation and immunity disorder models. (The product is for research purpose only.)

References


PubMed Literature


์ œํ’ˆ๊ธฐ์‚ฌ
์ œํ’ˆ๋ฌธ์„œ (๋ถ„์„ ์ฐจํŠธ๋ฅผ ์ œ๊ณตํ•˜์ง€ ๋ชปํ•  ์ˆ˜๋„ ์žˆ์œผ๋‹ˆ ์–‘ํ•ด ๋ฐ”๋ž๋‹ˆ๋‹ค.)
SDS
์–ธ์–ด๋ฅผ ์„ ํƒํ•˜์‹ญ์‹œ์˜ค.

์š”์ฒญํ•œ SDS๋ฅผ ์‚ฌ์šฉํ•  ์ˆ˜ ์—†์Šต๋‹ˆ๋‹ค.

๋ฒˆ๊ฑฐ๋กญ๊ฒŒ ํ•ด๋“œ๋ ค ์ฃ„์†กํ•˜์ง€๋งŒ ์ด ์–‘์‹ ๋ณด๋‹ค ๋ฌธ์˜ ํ•ด์ฃผ์‹ญ์‹œ์˜ค.

๊ทœ๊ฒฉํ‘œ
์‹œํ—˜์„ฑ์ ์„œ๏ผŒ ๊ฐ์ข… ์ฆ๋ช…์„œ
๋กฏํŠธ ๋ฒˆํ˜ธ๋ฅผ ์ž…๋ ฅํ•˜์‹ญ์‹œ์˜ค. ์ž˜๋ชป๋œ ๋กœํŠธ ๋ฒˆํ˜ธ๊ฐ€ ์ž…๋ ฅ๋˜์—ˆ์Šต๋‹ˆ๋‹ค.

๊ฒ€์ƒ‰ํ•˜์‹  ๋กœํŠธ ๋ฒˆํ˜ธ๋Š” ํ˜„์žฌ ์‚ฌ์šฉ์ด ๋ถˆ๊ฐ€๋Šฅํ•˜๋ฉฐ, ๊ด€๋ จ ๋ฌธ์„œ๋„ ์ œ๊ณต๋˜์ง€ ์•Š์Šต๋‹ˆ๋‹ค. ์ด ์ œํ’ˆ์— ๋Œ€ํ•ด์„œ๋Š” ๋‹ค๋ฅธ ๋กœํŠธ ๋ฒˆํ˜ธ๋ฅผ ์ž…๋ ฅํ•ด ์ฃผ์‹œ๊ธฐ ๋ฐ”๋ž๋‹ˆ๋‹ค.

์ƒ˜ํ”Œ ์‹œํ—˜์„ฑ์ ์„œ
์‹œํ—˜์„ฑ์ ์„œ ์ƒ˜ํ”Œ์„ ๋‹ค์šด๋กœ๋“œํ•  ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ์ƒ˜ํ”Œ์€ ๋ฐ˜๋“œ์‹œ ์ตœ์‹  ๋กœํŠธ์˜ ๊ฒฐ๊ณผ๋ฅผ ๋‚˜ํƒ€๋‚ด๋Š” ๊ฒƒ์€ ์•„๋‹™๋‹ˆ๋‹ค.

๋ณธ ์ œํ’ˆ์˜ ์ƒ˜ํ”Œ์‹œํ—˜์„ฑ์ ์„œ๋Š” ํ˜„์žฌ ์ค€๋น„๋˜์–ด ์žˆ์ง€ ์•Š์Šต๋‹ˆ๋‹ค.

๋ถ„์„ ์ฐจํŠธ
๋กฏํŠธ ๋ฒˆํ˜ธ๋ฅผ ์ž…๋ ฅํ•˜์‹ญ์‹œ์˜ค. ์ž˜๋ชป๋œ ๋กœํŠธ ๋ฒˆํ˜ธ๊ฐ€ ์ž…๋ ฅ๋˜์—ˆ์Šต๋‹ˆ๋‹ค.

์ฃ„์†กํ•ฉ๋‹ˆ๋‹ค๋งŒ ์ฐพ์œผ์‹œ๋Š” ๋ถ„์„์ฐจํŠธ๋Š” ์—†์Šต๋‹ˆ๋‹ค.

๊ฒ€์ƒ‰ํ•˜์‹  ๋กœํŠธ ๋ฒˆํ˜ธ๋Š” ํ˜„์žฌ ์‚ฌ์šฉ์ด ๋ถˆ๊ฐ€๋Šฅํ•˜๋ฉฐ, ๊ด€๋ จ ๋ฌธ์„œ๋„ ์ œ๊ณต๋˜์ง€ ์•Š์Šต๋‹ˆ๋‹ค. ์ด ์ œํ’ˆ์— ๋Œ€ํ•ด์„œ๋Š” ๋‹ค๋ฅธ ๋กœํŠธ ๋ฒˆํ˜ธ๋ฅผ ์ž…๋ ฅํ•ด ์ฃผ์‹œ๊ธฐ ๋ฐ”๋ž๋‹ˆ๋‹ค.

๊ธฐํƒ€ ์„œ๋ฅ˜

Life Science
์„ธ์…˜ ์ƒํƒœ
์„ธ์…˜์˜ ๋‚จ์€ ์‹œ๊ฐ„์€ 10๋ถ„์ž…๋‹ˆ๋‹ค. ์ด๋Œ€๋กœ ๋ฐฉ์น˜ํ•˜๋ฉด ์„ธ์…˜์ด ๋Š์–ด์ง€๊ณ  ํƒ‘ํŽ˜์ด์ง€๋กœ ๋Œ์•„๊ฐ‘๋‹ˆ๋‹ค. ๊ฐ™์€ ํŽ˜์ด์ง€์—์„œ ์„ธ์…˜์„ ๊ณ„์†ํ•˜๋ ค๋ฉด ๋ฒ„ํŠผ์„ ํด๋ฆญํ•˜์‹ญ์‹œ์˜ค.๋ถ„์ž…๋‹ˆ๋‹ค. ์ด๋Œ€๋กœ ๋ฐฉ์น˜ํ•˜๋ฉด ์„ธ์…˜์ด ๋Š์–ด์ง€๊ณ  ํƒ‘ํŽ˜์ด์ง€๋กœ ๋Œ์•„๊ฐ‘๋‹ˆ๋‹ค. ๊ฐ™์€ ํŽ˜์ด์ง€์—์„œ ์„ธ์…˜์„ ๊ณ„์†ํ•˜๋ ค๋ฉด ๋ฒ„ํŠผ์„ ํด๋ฆญํ•˜์‹ญ์‹œ์˜ค.

์„ธ์…˜์ด ์‹œ๊ฐ„ ์ดˆ๊ณผ๋˜์—ˆ์Šต๋‹ˆ๋‹ค. ํƒ‘ํŽ˜์ด์ง€๋กœ ๋Œ์•„๊ฐ‘๋‹ˆ๋‹ค.

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