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CAS RN: 67-97-0 | ์ ํ๋ฒํธ: C0314
Cholecalciferol
×
์๋/๋ถ์ ๋ฐฉ๋ฒ: >98.0%(HPLC)
๋์์ด์:
- 7-Dehydrocholesterol, activated
- Vitamin D3
์ ํ๋ฌธ์:
| ํฌ์ฅ๋จ์ | ๊ฐ๊ฒฉ | ๋น์ผ์ถ๊ณ | 2-3์ผ ์ด๋ด ์ถ๊ณ | ์ถ๊ฐ๋ก ํ์ํ ๊ฒฝ์ฐ |
์ถํ ์ ๋ณด
|
|---|---|---|---|---|---|
| 1G |
โฉ95,600
|
≥100 | 31 | ์ฃผ๋ฌธ ํ 2์ฃผ ์ ๋ ์์๋ฉ๋๋ค |
โข๋ณธ ์ ํ์ ์ฌ๊ณ ๋ ์ผ๋ณธ ๋ณธ์ฌ์ ์ฌ๊ณ ์
๋๋ค. ์ฃผ๋ฌธ์, 5์ผ์์ ์คํ์ค๊น์ง ๋์ฐฉ๋ฉ๋๋ค.
โข๋ณธ๊ฑด์ ์๊ฐ๊ฒฉ์ ํ๊ตญ ๋๋ฆฌ์ ์ ์์ ํ๋งค๊ฐ๊ฒฉ์ ๋๋ค.์์ธํ ์ ๋ณด๊ฐ ํ์ํ์๋ฉด ์ฐ๋ฝํด ์ฃผ์ญ์์ค.( SEJIN CI Co., Ltd. (ํ๊ตญ์ด๋๋ฆฌ์ ) ์ ํ : 02-2655-2480 ์ด๋ฉ์ผ : sales@sejinci.co.kr)
โข๋ณด๊ด ์กฐ๊ฑด์ ์๊ณ ์์ด ๋ณ๊ฒฝ ๋ ์ ์์ต๋๋ค. ์ ํ ๋ณด๊ด ์กฐ๊ฑด์ ์ต์ ์๋ฃ๋ ํํ์ด์ง์ ๊ธฐ์ฌ๋์ด ์์ผ๋ ์ํด ๋ถํ๋๋ฆฝ๋๋ค.
โข๋ณธ๊ฑด์ ์๊ฐ๊ฒฉ์ ํ๊ตญ ๋๋ฆฌ์ ์ ์์ ํ๋งค๊ฐ๊ฒฉ์ ๋๋ค.์์ธํ ์ ๋ณด๊ฐ ํ์ํ์๋ฉด ์ฐ๋ฝํด ์ฃผ์ญ์์ค.( SEJIN CI Co., Ltd. (ํ๊ตญ์ด๋๋ฆฌ์ ) ์ ํ : 02-2655-2480 ์ด๋ฉ์ผ : sales@sejinci.co.kr)
โข๋ณด๊ด ์กฐ๊ฑด์ ์๊ณ ์์ด ๋ณ๊ฒฝ ๋ ์ ์์ต๋๋ค. ์ ํ ๋ณด๊ด ์กฐ๊ฑด์ ์ต์ ์๋ฃ๋ ํํ์ด์ง์ ๊ธฐ์ฌ๋์ด ์์ผ๋ ์ํด ๋ถํ๋๋ฆฝ๋๋ค.
| ์ ํ๋ฒํธ | C0314 |
Purity/Analysis Method 
|
>98.0%(HPLC) |
| M.F. / M.W. | C__2__7H__4__4O = 384.65 |
| ๋ฌผ๋ฆฌ์ ์ํ (20 โ) | Solid |
| ๋ณด๊ด ์กฐ๊ฑด
|
Frozen (<0ยฐC) |
| ๋ถํ์ฑ ๊ฐ์ค ํ์์ ๋ณด๊ด | Store under inert gas |
| ํผํด์ผ ํ ์กฐ๊ฑด | Air Sensitive,Heat Sensitive |
| ์ฉ๊ธฐ
|
1G-Glass Bottle with Plastic Insert (์ด๋ฏธ์ง ๋ณด๊ธฐ) |
| CAS RN | 67-97-0 |
| PubChem Substance ID | 125308742 |
| SDBS | 10003 |
| Merck Index (14) | 10019 |
| MDL ๋ฒํธ | MFCD00078131 |
๊ท๊ฒฉํ
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +103 to +112 deg(C=0.5, EtOH) |
| Absorbance | 0.450 to 0.510(10mg/L, EtOH, 263.0 to 267.0 nm) |
| NMR | confirm to structure |
๋ฌผ์ฑ์น(์ฐธ๊ณ ์น)
| mp | 86 ยฐC |
| ๋น์จ ๊ดํ ํ์ [ฮฑ]D | 108ยฐ (C=0.5,EtOH) |
| Solubility in water | Insoluble |
| ์ฉํด์ฑ (์ฉํด) | Alcohol, Chloroform |
GHS
| ํฝํ ๊ทธ๋จ |
|
| ์ ํธ ์๋ | Danger |
| ์ํ๋ฌผ ๋ฐ ์ ํด ๋ฑ๋ก | H300 + H310 + H330 : Fatal if swallowed, in contact with skin or if inhaled. H360 : May damage fertility or the unborn child. H372 : Causes damage to organs through prolonged or repeated exposure. H413 : May cause long lasting harmful effects to aquatic life. |
| ์ฃผ์ ์ฌํญ | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P260 : Do not breathe dust. P270 : Do not eat, drink or smoke when using this product. P262 : Do not get in eyes, on skin, or on clothing. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P284 : Wear respiratory protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P361 + P364 : Take off immediately all contaminated clothing and wash it before reuse. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P302 + P352 + P310 : IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/doctor. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
๋ฒ๊ท ์ ๋ณด
| RTECS # | VS2900000 |
์ด์ก ์ ๋ณด
| UN ๋ฒํธ | UN2811 |
| ๋ฑ๊ธ | 6.1 |
| ํฌ์ฅ ๊ทธ๋ฃน | II |
| HS ๋ฒํธ* | 2936.29-000 |
Application
Efflux pump inhibitor
References
- Action of cholecalciferol and alpha-tocopherol on Staphylococcus aureus efflux pumps
Application
Cholecalciferol (Vitamin D3): A Compound for the Maintenance of Normal Skeleton Architecture and Mineral Homeostasis
Cholecalciferol (Vitamin D3) is known for the maintenance of normal skeleton architecture and mineral homeostasis. Vitamin D3 is synthesized from 7-dehydrocholesterol [CAS: 434-16-2] in the skin under the influence of UV light, or it is obtained from food, especially fatty fish. The transformation (hydroxylation) of vitamin D3 is catalyzed by enzymes in the liver and the kidney to produce calcitriol [C3078] (other name: 1α,25-dihydroxyvitamin D3), the active form of vitamin D3. Calcitriol is active in the regulation of the absorption of calcium from the gastrointestinal tract. (The product is for research purpose only.)
References
- Overview of general physiologic features and functions of vitamin D (a review)
- Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease (a review)
- Enzymes involved in the activation and inactivation of vitamin D (a review)
- Vitamin D physiology (a review)
- Analytical measurement and clinical relevance of vitamin D3 C3-epimer (a review)
- The role of vitamin D in reducing cancer risk and progression (a review)
PubMed Literature
๋ฌธ์
์ ํ๊ธฐ์ฌ
์ ํ๋ฌธ์ (๋ถ์ ์ฐจํธ๋ฅผ ์ ๊ณตํ์ง ๋ชปํ ์๋ ์์ผ๋ ์ํด ๋ฐ๋๋๋ค.)
SDS
์ธ์ด๋ฅผ ์ ํํ์ญ์์ค.
์์ฒญํ SDS๋ฅผ ์ฌ์ฉํ ์ ์์ต๋๋ค.
๋ฒ๊ฑฐ๋กญ๊ฒ ํด๋๋ ค ์ฃ์กํ์ง๋ง ์ด ์์ ๋ณด๋ค ๋ฌธ์ ํด์ฃผ์ญ์์ค.
๊ท๊ฒฉํ
์ํ์ฑ์ ์๏ผ ๊ฐ์ข ์ฆ๋ช ์
๋กฏํธ ๋ฒํธ๋ฅผ ์
๋ ฅํ์ญ์์ค.
์๋ชป๋ ๋กํธ ๋ฒํธ๊ฐ ์
๋ ฅ๋์์ต๋๋ค.
์ํ ์ํ์ฑ์ ์
์ํ์ฑ์ ์ ์ํ์ ๋ค์ด๋ก๋ํ ์ ์์ต๋๋ค. ์ํ์ ๋ฐ๋์ ์ต์ ๋กํธ์ ๊ฒฐ๊ณผ๋ฅผ ๋ํ๋ด๋ ๊ฒ์ ์๋๋๋ค.
๋ณธ ์ ํ์ ์ํ์ํ์ฑ์ ์๋ ํ์ฌ ์ค๋น๋์ด ์์ง ์์ต๋๋ค.
๋ถ์ ์ฐจํธ
๋กฏํธ ๋ฒํธ๋ฅผ ์
๋ ฅํ์ญ์์ค.
์๋ชป๋ ๋กํธ ๋ฒํธ๊ฐ ์
๋ ฅ๋์์ต๋๋ค.
์ฃ์กํฉ๋๋ค๋ง ์ฐพ์ผ์๋ ๋ถ์์ฐจํธ๋ ์์ต๋๋ค.