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Useful Compound for Synthesis of Chiral Biphenyl Ligands
No.153(December 2014)

2-Iodo-3-nitrotoluene (1) is a useful compound for synthesis of atropisometric biphenyl backbones, which are widely used as chiral ligands.
References
- 1)K. M. Gillespie, C. J. Sanders, P. O'Shaughnessy, I. Westmoreland, C. P. Thickitt, P. Scott, J. Org. Chem. 2002, 67, 3450.
- 2)Y. Liang, S. Gao, H. Wan, J. Wang, H. Chen, Z. Zheng, X. Hu, Tetrahedron: Asymmetry 2003, 14, 1267.
- 3)A. Miyashita, H. Karino, J. Shimamura, T. Chiba, K. Nagano, H. Nohira, H. Takaya, Chem. Lett. 1989, 18, 1849.
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