Maximum quantity allowed is 999
Please select the quantity
CAS RN: 255906-59-3 | Product Number: V0173
VK3-OCH3
Purity: >98.0%(HPLC)
Synonyms:
- 2-[(2-Methoxyethyl)thio]-3-methylnaphthalene-1,4-dione
- 2-[(2-Methoxyethyl)thio]-3-methyl-1,4-naphthoquinone
- 2-(2-Methoxyethylsulfanyl)-3-methylnaphthalene-1,4-dione
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days |
---|---|---|---|
50MG |
₩555,000
|
17 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Product Number | V0173 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C__1__4H__1__4O__3S = 262.32 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
CAS RN | 255906-59-3 |
Reaxys Registry Number | 35070670 |
PubChem Substance ID | 468593116 |
MDL Number | MFCD22575003 |
Specifications
Appearance | Light yellow to Yellow to Orange powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Melting point | 66.0 to 70.0 °C |
NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
Transport Information:
H.S.code* | 2930.90-900 |
Application
VK3-OCH3: A Thioether Analog of Vitamin K with a Selective Anti-Tumor Activity
VK3-OCH3 is a thioether analog of vitamin K with a selective anti-tumor activity.1-3) It has been reported that VK3-OCH3 inhibits the activity of protein-tyrosine phosphatases (PTPases), and induces protein-tyrosine phosphorylation in a human hepatoma cell line (Hep3 B).1) In another report, VK3-OCH3 induces G2/M arrest and apoptosis through heme oxygenase-1 (HO-1) related signal transduction in neuroblastoma cells and exhibit less cytotoxicitiy in normal cell lines.2) (The product is for research purpose only.)
References
- 1) Inhibition of hepatoma cell growth in vitro by arylating and non-arylating K vitamin analogs. Significance of protein tyrosine phosphatase inhibition
- 2) Vitamin K3 Analogs Induce Selective Tumor Cytotoxicity in Neuroblastoma
- 3) Synthesis, anticancer activity, and molecular modeling of 1,4-naphthoquinones that inhibit MKK7 and Cdc25
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.