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CAS RN: 530-78-9 | Product Number: T2354
2-(3-Trifluoromethylanilino)benzoic Acid
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 2-[(3-Trifluoromethylphenyl)amino]benzoic Acid
- N-(3-Trifluoromethylphenyl)anthranilic Acid
- Flufenamic Acid
Product Documents:
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* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Product Number | T2354 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__4H__1__0F__3NO__2 = 281.23 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
CAS RN | 530-78-9 |
Reaxys Registry Number | 1996069 |
PubChem Substance ID | 87558841 |
Merck Index (14) | 4132 |
MDL Number | MFCD00002422 |
Specifications
Appearance | White to Light yellow to Green powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
Melting point | 133.0 to 137.0 °C |
Properties (reference)
Melting Point | 135 °C |
Solubility (soluble in) | Methanol |
GHS
Pictogram |
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Signal Word | Danger |
Hazard Statements | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
RTECS# | CB4375000 |
Transport Information:
UN Number | UN2811 |
Class | 6.1 |
Packing Group | III |
H.S.code* | 2922.49-000 |
Application
Flufenamic acid: An Ion Channel Modulator
Flufenamic acid has been known as a non-steroidal anti-inflammatory agent since the 1960s which can interfere with prostaglandin synthesis. Recently, flufenamic acid has been reported as an ion channel (e.g. TRPM) modulator. TRPM (transient receptor potential melastatin) is a family of transient receptor potential ion channels which play critical roles in mediating cellular responses to a wide range of physiological stimuli that can induce cell death. (The product is for research purpose only.)
References
- The role of TRPM channels in cell death (a review)
- TRPM2 Cation Channels, Oxidative Stress and Neurological Diseases: Where Are We Now? (a review)
- Flufenamic acid as an ion channel modulator (a review)
- Flufenamic acid (a review on the properties, synthesis, metabolism, pharmacology, and methods of detection)
- Determination of diclofenac sodium, flufenamic acid, indomethacin and ketoprofen by LC-APCI-MS
PubMed Literature
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TCIMAIL
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