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CAS RN: 66-32-0 | Product Number: S0093
Strychnine Nitrate
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Purity: >99.0%(T)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25G |
₩151,700
|
39 | 4 | It can be shipped in about 2 weeks after ordering |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | S0093 |
| Purity / Analysis Method | >99.0%(T) |
| Molecular Formula / Molecular Weight | C__2__1H__2__2N__2O__2·HNO__3 = 397.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive |
| CAS RN | 66-32-0 |
| Reaxys Registry Number | 4919459 |
| PubChem Substance ID | 87575708 |
| Merck Index (14) | 8855 |
| MDL Number | MFCD00078519 |
Specifications
| Appearance | White powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 99.0 % |
| Solubility in hot Water | almost transparency |
| NMR | confirm to structure |
Properties (reference)
| Solubility in water | Soluble |
| Solubility (soluble in) | Chloroform |
| Solubility (slightly sol. in) | Ethanol |
| Solubility (insoluble in) | Ether |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H300 : Fatal if swallowed. H370 : Causes damage to organs. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | WL2450000 |
Transport Information:
| UN Number | UN1692 |
| Class | 6.1 |
| Packing Group | I |
| H.S.code* | 2939.79-000 |
Application
Strychnine: An Indole Alkaloid with Antagonistic Activity toward Glycine and Acetylcholine Receptors
Strychnine [S0249] is an indole alkaloid obtained from the seeds and bark of Strychnos nux-vomica, has been used as a rodenticide for more than a century. Glycine is an inhibitory transmitter to motor neurons and interneurons in the spinal cord. Strychnine is a neurotoxin which acts as an antagonist of glycine and acetylcholine receptors, resulting in disinhibition of motor neurons in the spinal cord.1,2) In addition, strychnine has been a target compound for total synthesis since it was first synthesized by the group of R. B. Woodward in 1954.3,4) Strychnine is poorly soluble in water, but its sulfate [S0094], nitrate [S0093] and hydrochloride [S0257] are moderately soluble in water. (The product is for research purpose only.)
References
- 1) The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors
- 2) Inhibitory glycine receptors: an update (a review)
- 3) Synthesis of Strychnine (a review)
- 4) Is There No End to the Total Syntheses of Strychnine? Lessons Learned in Strategy and Tactics in Total Synthesis
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