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CAS RN: 144875-48-9 | Product Number: R0197
Resiquimod
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Purity: >98.0%(HPLC)
Synonyms:
- 1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
₩222,000
|
0 | 4 | It can be shipped in about 2 weeks after ordering | |
| 100MG |
₩651,200
|
16 | 26 | It can be shipped in about 2 weeks after ordering |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | R0197 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__2__2N__4O__2 = 314.39 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic,Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 144875-48-9 |
| Reaxys Registry Number | 9792901 |
| PubChem Substance ID | 354335079 |
| Merck Index (14) | 8151 |
| MDL Number | MFCD00937759 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
Properties (reference)
| Melting Point | 193 °C |
| Maximum Absorption Wavelength | 325 nm |
GHS
Related Laws:
| RTECS# | NJ5911320 |
Transport Information:
| H.S.code* | 2933.99-000 |
Application
Resiquimod: A Toll-Like Receptor Agonist
Resiquimod (R-848) is a tricyclic imidazoquinolone compound and an imiquimod [I0747] analog. Toll-like receptors (TLRs) play an important role in the innate immune response to pathogens. Reportedly, resiquimod act as an immunomodulator and an anti-viral agent through activation immune cells via the Toll-like receptor 7 and 7/8 (TLR7 and TLR7/8) dependent signaling pathway. And then, resiquimod induces mRNA encoding cytokines including interferon-α (INF-α) at the treatment site. (The product is for research purpose only.)
References
- Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
- Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848
- Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
- The antiviral activity of toll-like receptor 7 and 7/8 agonists (a review)
- The use of Toll-like receptor 7/8 agonists as vaccine adjuvants (a review)
PubMed Literature
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