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CAS RN: 20554-84-1 | Product Number: P1982
Parthenolide
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Purity: >97.0%(HPLC)
Synonyms:
- 4,5α-Epoxy-6β-hydroxygermacra-1(10),11(13)-dien-12-oic Acid γ-Lactone
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
₩162,800
|
24 | 3 | Contact Us | |
| 100MG |
₩427,400
|
2 | 21 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | P1982 |
| Purity / Analysis Method | >97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__2__0O__3 = 248.32 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 20554-84-1 |
| Reaxys Registry Number | 17582 |
| PubChem Substance ID | 135727274 |
| Merck Index (14) | 7048 |
| MDL Number | MFCD00134592 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Specific rotation [a]20/D | -81.0 to -86.0 deg(C=1, CHCl3) |
Properties (reference)
| Melting Point | 115 °C |
| Specific Rotation | -84° (C=1,CHCl3) |
| Solubility (soluble in) | Chloroform |
GHS
Related Laws:
| RTECS# | LY4220000 |
Transport Information:
| H.S.code* | 2932.99-000 |
Application
Type IV secretion system (T4SS) research
Reference
- Chemical Genetics Reveals Bacterial and Host Cell Functions Critical for Type IV Effector Translocation by Legionella pneumophila
Application
Parthenolide: A Sesquiterpene Lactone with Potent Anticancer and Anti-Inflammatory Activities
Parthenolide, a sesquiterpene lactone, is originally isolated from the shoots of feverfew (Tanacetum parthenium) which is a traditional medical plant used commonly to prevent migraine headaches. Parthenolide has been reported to show potent anticancer and anti-inflammatory activities. For example, parthenolide inhibits the transcription factor NF-κB, and induces apoptosis of human acute myelogenous leukemia stem and progenitor cells. (The product is for research purpose only.)
References
- The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-κB by targeting the IκB kinase complex
- The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IκB kinase
- The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
- Parthenolide, a Sesquiterpene Lactone, Expresses Multiple Anti-cancer and Anti-inflammatory Activities (a review)
- Parthenolide: from plant shoots to cancer roots (a review)
PubMed Literature
Articles/Brochures
TCIMAIL
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Specifications
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