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CAS RN: 484-12-8 | Product Number: O0426
Osthole
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Purity: >98.0%(GC)
Synonyms:
- 7-Methoxy-8-(3-methyl-2-butenyl)coumarin
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 250MG |
₩33,300
|
17 | 4 | Contact Us | |
| 1G |
₩98,100
|
0 | 4 | Contact Us | |
| 5G |
₩342,300
|
0 | 14 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | O0426 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__6O__3 = 244.29 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 484-12-8 |
| Reaxys Registry Number | 1288399 |
| PubChem Substance ID | 253662100 |
| Merck Index (14) | 6895 |
| MDL Number | MFCD00076049 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 82.0 to 86.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 84 °C |
| Maximum Absorption Wavelength | 322(MeOH) nm |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Ethanol |
GHS
Related Laws:
| RTECS# | GN7700000 |
Transport Information:
| H.S.code* | 2932.20-000 |
Application
Efflux pump inhibitor
References
- Osthol and curcumin as inhibitors of human Pgp and multidrug efflux pumps of Staphylococcus aureus: Reversing the resistance against frontline antibacterial drugs
Application
A Crude Drug Ingredient in Cnidii Monnieri Fructus and etc.
Osthol is a natural coumarin that found in a variety of plants including Cnidium monnieri, Angelica archangelica and Angelica pubescens. Osthol is an ingredient of a Traditional Chinese Medicine (TCM), and has received attention recently because of its significant and diverse pharmacological activities, including anticancer, anti-osteoporotic, and anti-proliferative activities. (The product is for research purpose only.)
References
- Osthole-mediated cell differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway in human osteoblast cells
- Anti-allergic effects of Cnidii Monnieri Fructus (dried fruits of Cnidium monnieri) and Iits major component, osthol
- Coumarins from Cnidium monnieri and their antiosteoporotic activity
- Antitumor effects of Osthol from Cnidium monnieri: an in vitro and in vivo study
- Osthole: a promising lead compound for drug discovery from a Traditional Chinese Medicine (TCM) (a review)
- Potential Anticancer Properties of Osthol: A Comprehensive Mechanistic Review
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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