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CAS RN: 77086-22-7 | Product Number: M3393
(+)-MK 801 Maleate
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Purity: >98.0%(HPLC)
Synonyms:
- (5S,10R)-5-Methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene Maleate
- Dizocilpine Maleate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
₩303,400
|
9 | 15 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | M3393 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__5N·C__4H__4O__4 = 337.38 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| Packaging and Container | 25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 77086-22-7 |
| Reaxys Registry Number | 7158220 |
| PubChem Substance ID | 468592439 |
| MDL Number | MFCD00082465 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation | +115 to +121 deg(C=0.6, ｴﾀﾉｰﾙ) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 210 °C |
GHS
Related Laws:
| RTECS# | HP1093575 |
Transport Information:
| H.S.code* | 2933.49-000 |
Application
(+)-MK 801 maleate: A Potent, Selective and Non-Competitive N-methyl-D-aspartate (NMDA) receptor antagonist
(+)-MK 801 maleate (its other name: dizocilpine maleate) is a potent, selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist, and has been reported to display various physiological effects, mainly involving the central nervous system.1-3) Therefore, (+)-MK 801 maleate has been used as an important tool for the screening of antipsychotic potential of new compounds.4) (The product is for research purpose only.)
References
- 1) The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist
- 2) Inhibition of morphine tolerance and dependence by the NMDA receptor antagonist MK-801
- 3) Clinical physiology and mechanism of dizocilpine (MK-801): electron transfer, radicals, redox metabolites and bioactivity (a review)
- 4) Consequences of early life MK-801 administration: Long-term behavioural effects and relevance to schizophrenia research (a review)
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