Maintenance Notice (3:15 - 7:30 AM February 22, 2025 UTC): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Notice of Discontinuing the Use of Password-Protected Compressed Files | Product Document Searching Made Easy by 2D Code! | TCI Life Science News February 2025 | [Product Highlights] Chemiluminescent Reagents for... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 29216-28-2 | Product Number: M2807
Mequitazine
×
![]()
×
Purity: >98.0%(GC)(T)
Synonyms:
- 10-(Quinuclidin-3-ylmethyl)-10H-phenothiazine
- 10-(1-Azabicyclo[2.2.2]oct-3-ylmethyl)-10H-phenothiazine
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
₩48,100
|
3 | 33 | Contact Us | |
| 1G |
₩275,700
|
12 | 0 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | M2807 |
| Purity / Analysis Method | >98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__2__0H__2__2N__2S = 322.47 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 29216-28-2 |
| Reaxys Registry Number | 1150945 |
| PubChem Substance ID | 354333324 |
| Merck Index (14) | 5864 |
| MDL Number | MFCD01706743 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 146.0 to 150.0 °C |
Properties (reference)
| Melting Point | 148 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Ethanol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | SP5080000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| H.S.code* | 2934.30-000 |
Application
長時間持続性の選択的ヒスタミンH1-受容体アンタゴニスト，メキタジン
Mequitazine is a long-acting and selective histamine H1-receptor antagonist. Mequitazine also possesses antagonistic activity for leukotrienes (LTs) and platelet activating factor (PAF). In the inhibition process, mequitazine acts to inhibit the Ca2+ release from intracellular calcium store of mast cells. Mequitazine is mainly biotransformed by cytochrome P450 2D6 (CYP2D6) in human liver to yield aromatic hydroxylated and S-oxidized metabolites.
References
- Anti-platelet activating factor, anti-leukotriene D4 and some other antiallergic activities of mequitazine.
- Possible mechanisms of vasoinhibitory effects of mequitazine, an antiallergic agent, on the contractions of isolated rat aorta induced by K+, phenylephrine, 5-hydroxytryptamine, and Ca2+.
- Oxidation of Histamine H1 Antagonist Mequitazine is Catalyzed by Cytochrome P450 2D6 in Human Liver Microsomes
- Pipette tip solid-phase extraction and gas chromatography-mass spectrometry for the determination of mequitazine in human plasma
- Pharmacological study of Mequitazine (LM-209) (II) Anti-allergic action [Article in Japanese]
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.