Maximum quantity allowed is 999
Please select the quantity
CAS RN: 6964-62-1 | Product Number: M2390
NSC 66811
×
![]()
×
Purity: >98.0%(GC)
Synonyms:
- 8-Hydroxy-2-methyl-7-[phenyl(phenylamino)methyl]quinoline
- 2-Methyl-7-[phenyl(phenylamino)methyl]-8-quinolinol
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 25MG |
₩264,600
|
7 | 1 |
| 100MG |
₩790,000
|
15 | 13 |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | M2390 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__2__3H__2__0N__2O = 340.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 6964-62-1 |
| Reaxys Registry Number | 303275 |
| PubChem Substance ID | 354335381 |
| MDL Number | MFCD08823776 |
Specifications
| Appearance | White to Amber to Dark green powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 96.0 % |
| Melting point | 143.0 to 147.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 145 °C |
| Maximum Absorption Wavelength | 250(EtOH) nm |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.49-000 |
Application
NSC 66811: An Inhibitor of MDM2-P53 Protein-Protein Interaction
NSC 66811 is an inhibitor of the murine double minute 2 (MDM2)-p53 protein-protein interaction. MDM2 protein is an oncogenic one, and p53 is a tumor suppressor protein. Reportedly, the p53 is inactivated in many cancer cells through mutations or by its interaction with MDM2 protein. Therefore, recently it is considered that blocking the MDM2-p53 interaction is a novel anticancer strategy. (The product is for research purpose only.)
References
- Unleashing p53 (a review)
- Discovery of a Nanomolar Inhibitor of the Human Murine Double Minute 2 (MDM2)-p53 Interaction through an Integrated, Virtual Database Screening Strategy
- Case Study: Discovery of Inhibitors of the MDM2-p53 Protein-Protein Interaction
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.