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CAS RN: 85999-40-2 | Product Number: H1742
23-Hydroxybetulinic Acid

Purity: >98.0%(HPLC)
Synonyms:
- Anemosapogenin
- 3β,23-Dihydroxylup-20(29)-en-28-oic Acid
- (1R,3aS,5aR,5bR,7aR,8R,9S,11aR,11bR,13aR,13bR)-9-Hydroxy-8-(hydroxymethyl)-5a,5b,8,11a-tetramethyl-1-(prop-1-en-2-yl)icosahydro-3aH-cyclopenta[a]chrysene-3a-carboxylic Acid
Product Documents:
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* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Product Number | H1742 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C__3__0H__4__8O__4 = 472.71 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Frozen (-20°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Light Sensitive,Moisture Sensitive,Heat Sensitive |
CAS RN | 85999-40-2 |
Reaxys Registry Number | 8178643 |
PubChem Substance ID | 468592022 |
MDL Number | MFCD28126999 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(HPLC)(CAD) | min. 98.0 area% |
NMR | confirm to structure |
Properties (reference)
Melting Point | 305 °C |
Specific Rotation | 19° (C=1,CH2Cl2) |
GHS
Related Laws:
Transport Information:
H.S.code* | 2918.19-000 |
Application
23-Hydroxybetulinic Acid: A Pentacyclic Triterpene with Anti-Tumor Activities
23-Hydroxybetulinic acid (23-HBA) is a pentacyclic triterpene is the major active constituent of Pulsatilla chinensis (Bunge) Regel used as an anti-inflammatory agent in traditional Chinese medicine. It has been reported that 23-HBA and its derivatives show a cytotoxic effect on multiple cancer cell lines. (The product is for research purpose only.)
References
- Triterpenoids from Pulsatilla chinensis
- A sensitive HPLC-MS/MS method for the simultaneous determination of anemoside B4, anemoside A3 and 23-hydroxybetulinic acid: Application to the pharmacokinetics and liver distribution of Pulsatilla chinensis saponins
- 23-Hydroxybetulinic acid-mediated apoptosis is accompanied by decreases in bcl-2 expression and telomerase activity in HL-60 Cells
- 23-Hydroxybetulinic acid from Pulsatilla chinensis (Bunge) Regel synergizes the antitumor activities of doxorubicin in vitro and in vivo
- Recent developments in the functionalization of betulinic acid and its natural analogues: a route to new bioactive compounds (a review)
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