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CAS RN: 58546-54-6 | Product Number: G0537
Gomisin A
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Purity: >96.0%(HPLC)
Synonyms:
- Schisandrol B
- Besigomsin
- (6S,7S)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
- (6S,7S,13aR)-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 5MG |
₩275,700
|
10 | 22 | It can be shipped in about 3-4 weeks after ordering | |
| 25MG |
₩1,002,700
|
15 | 25 | It can be shipped in about 3-4 weeks after ordering |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | G0537 |
| Purity / Analysis Method | >96.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__3H__2__8O__7 = 416.47 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 58546-54-6 |
| Reaxys Registry Number | 1299162 |
| PubChem Substance ID | 468591921 |
| MDL Number | MFCD01941645 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 96.0 area% |
| Melting point | 91.0 to 95.0 °C |
| Specific rotation [a]20/D | +67.0 to +73.0 deg(C=1, CHCl3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 93 °C |
| Specific Rotation | 70° (C=1,CHCl3) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | DE8396900 |
Transport Information:
| H.S.code* | 2932.99-000 |
Application
Gomisin A: A Lignan Contained in the Dried Fruits of Schizandra chinensis
Gomisin A (schisandrol B) is a lignan contained in the dried fruits of Schizandra chinensis (Schisandraceae) which is a traditional medicine used as an antitussive and a tonic.1,2) It has been reported that gomisin A possesses various pharmacological activities, such as anti-inflammatory, antihypertensive, neuroprotective, and anti-proliferation properties.3-5) In addition, gomisin A has protective activity against hepatic and renal injury induced by substances, such as acetaminophen and carbon tetrachloride.6,7) (The product is for research purpose only.)
References
- 1) The constituents of Schisandra chinensis Baill. I. Isolation and structure determination of five new lignans, gomisin A, B, C, F and G, and the absolute structure of schizandrin
- 2) A simple and sensitive HPLC method for the simultaneous determination of eight bioactive components and fingerprint analysis of Schisandra sphenanthera
- 3) Pharmacological studies on schizandra fruit. I. General pharmacological effects of gomisin A and schizandrin (in Japanese, its abstract in English.)
- 4) Gomisin A alters substrate interaction and reverses P-glycoprotein-mediated multidrug resistance in HepG2-DR cells
- 5) Gomisin A improves scopolamine-induced memory impairment in mice
- 6) Preventive effect of gomisin A, a lignan component of shizandra fruits, on acetaminophen-induced hepatotoxicity in rats
- 7) Pharmacological studies on schizandra fruits. II. Effects of constituents of shizandra fruits on chemical-induced hepatic damage in rats (in Japanese, its abstract in English.)
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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