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CAS RN: 144143-96-4 | Product Number: E1161
Eprosartan Mesylate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- Eprosartan Methanesulfonate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
₩77,700
|
3 | 2 | Contact Us | |
| 1G |
₩273,800
|
1 | 7 | Contact Us |
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* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | E1161 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__3H__2__4N__2O__4S·CH__4O__3S = 520.62 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 144143-96-4 |
| Related CAS RN | 133040-01-4 |
| Reaxys Registry Number | 27406159 |
| PubChem Substance ID | 253661215 |
| Merck Index (14) | 3635 |
| MDL Number | MFCD08141807 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 246.0 to 250.0 °C |
Properties (reference)
| Melting Point | 248 °C |
| Solubility in water | Insoluble |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | XN0282400 |
Transport Information:
| H.S.code* | 2934.99-000 |
Application
Eprosartan mesylate: A Long-Lasting and Selective Angiotensin II Subtype 1 (AT1) Receptor Antagonist (Saltan)
Eprosartan mesylate (SKF 108566) is a potent, long-lasting and non-peptide selective angiotensin II subtype 1 (AT1) receptor antagonist (Saltan). Blocking of the AT1 receptor by a saltan (e.g. valsartan [V0112], irbesartan [I0859], eprosartan mesylate [E1161] and losartan potassium [L0232]) suppresses the action of angiotensin II which increases blood pressure in various ways. Eprosartan is not metabolized by the cytochrome P 450 system and therefore has a low potential for drug interactions. Eprosartan mesylate is used in the treatment of hypertension. (The product is for research purpose only.)
References
- Pharmacological characterization of the nonpeptide angiotensin II receptor antagonist, SK&F 108566
- Differential inhibition of the prejunctional actions of angiotensin II in rat atria by valsartan, irbesartan, eprosartan, and losartan
- Angiotensin II AT1 Receptor Antagonists. (a review)
- Eprosartan: a review of its use in the management of hypertension
- Simultaneous determination of hydrochlorothiazide and several angiotensin-II-receptor antagonists by capillary electrophoresis
- Analytical techniques for estimation of eprosartan mesylate: an overview
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