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CAS RN: 5116-24-5 | Product Number: D6190
2'-Deoxy-5-(hydroxymethyl)uridine
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Purity: >98.0%(T)(HPLC)
Synonyms:
- α-Hydroxythymidine
- 5-Hydroxymethyl-2'-deoxyuridine
- 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 50MG |
₩236,800
|
3 | 0 | Contact Us | |
| 200MG |
₩723,400
|
0 | 11 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | D6190 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__4N__2O__6 = 258.23 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 5116-24-5 |
| Reaxys Registry Number | 31615 |
| MDL Number | MFCD00047489 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 179 °C |
GHS
Related Laws:
| RTECS# | YU7600000 |
Transport Information:
| H.S.code* | 2934.99-000 |
Application
2'-Deoxy-5-(hydroxymethyl)uridine: A Base-Modified 2’-Deoxynucleoside Used in Oxidative Stress and Cancer Studies
2'-Deoxy-5-(hydroxymethyl)uridine is a base-modified 2’-deoxynucleoside with anticancer and antiviral activities.1,2) It also acts as a diagnostic biomarker for oxidative stress in mammalian cells.3,4) Therefore, it has been reported to be used as an indicator of cancer. (The product is for research purpose only.)
References
- 1) Synthesis and biological activities of 5-(hydroxymethyl, azidomethyl, or aminomethyl)-2'-deoxyuridine and related 5'-substituted analogs
- 2) Synergistic enhancement of 5-fluorouracil cytotoxicity by deoxyuridine analogs in cancer cells
- 3) Effect of blueberry ingestion on natural killer cell counts, oxidative stress, and inflammation prior to and after 2.5 h of running
- 4) The Multiple Cellular Roles of SMUG1 in Genome Maintenance and Cancer (a review)
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