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CAS RN: 177355-84-9 | Product Number: D5476
DBeQ
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Purity: >98.0%(HPLC)
Synonyms:
- N,N'-Dibenzylquinazoline-2,4-diamine
Product Documents:
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* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Product Number | D5476 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C__2__2H__2__0N__4 = 340.43 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
CAS RN | 177355-84-9 |
Reaxys Registry Number | 7440169 |
PubChem Substance ID | 354335589 |
MDL Number | MFCD03691820 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Elemental analysis(Nitrogen) | 15.50 to 17.00 % |
Melting point | 147.0 to 151.0 °C |
NMR | confirm to structure |
Properties (reference)
Melting Point | 149 °C |
GHS
Related Laws:
Transport Information:
H.S.code* | 2933.99-000 |
Application
DBenQ: A Selective Reversible, and ATP-Competitive p97 Inhibitor
DBenQ has been reported as a selective reversible, and ATP-competitive p97 inhibitor. p97 is an important cellular AAA (ATPases associated with diverse cellular activities) ATPase, and is shown to play a critical role in the degradation of misfolded membrane and secretory proteins and also is linked to a broad array of cellular processes. Therefore, selective p97 inhibitors are valuable research tools to carry out mechanistic and cellular investigations of p97 biology.
References
- Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways
- Development of p97 AAA ATPase inhibitors (a review)
PubMed Literature
Articles/Brochures
TCIMAIL
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