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CAS RN: | Product Number: B6160
BGP-15 Hydrochloride
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Purity: >98.0%(HPLC)
Synonyms:
- N-[2-Hydroxy-3-(piperidin-1-yl)propoxy]nicotinimidamide Hydrochloride
- N-[2-Hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidamide Hydrochloride
- NP-51 Hydrochloride
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 5MG |
₩210,900
|
22 | 4 | It can be shipped in about 2 weeks after ordering | |
| 25MG |
₩740,000
|
32 | 0 | It can be shipped in about 2 weeks after ordering |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | B6160 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__4H__2__2N__4O__2·xHCl |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
| Related CAS RN | 459809-32-6&66611-37-8 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 200.0 to 204.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 202 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.39-000 |
Application
BGP-15: A PARP Inhibitor and an Insulin Sensitizer
Poly (ADP-ribose) polymerases (PARPs) is a family of enzymes involved in a number of cellular processes such as DNA repair, genomic stability, and apoptosis.1) BGP-15 has been used in cancer research because of its PARP inhibition.2) In addition, BGP-15 has recently reported as a pharmacological inducer of heat shock protein 72 (HSP72) and a new insulin sensitizer agent candidate.3,4) (The product is for research purpose only.)
References
- 1) Role of PARP Inhibitors in Cancer Biology and Therapy
- 2) Effect of Poly(ADP-Ribose) Polymerase Inhibitors on the Ischemia-Reperfusion-Induced Oxidative Cell Damage and Mitochondrial Metabolism in Langendorff Heart Perfusion System
- 3) HSP72 protects against obesity-induced insulin resistance
- 4) Pharmacological overview of the BGP-15 chemical agent as a new drug candidate for the treatment of symptoms of metabolic syndrome
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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