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CAS RN: 55-21-0 | Product Number: B0012
Benzamide
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Purity: >99.0%(N)
Synonyms:
- Benzoylamide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25G |
₩40,700
|
26 | ≥40 | It can be shipped in about 2 weeks after ordering | |
| 500G |
₩244,200
|
4 | 3 | It can be shipped in about 2 weeks after ordering |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | B0012 |
| Purity / Analysis Method | >99.0%(N) |
| Molecular Formula / Molecular Weight | C__7H__7NO = 121.14 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 55-21-0 |
| Reaxys Registry Number | 385876 |
| PubChem Substance ID | 87563226 |
| SDBS (AIST Spectral DB) | 1689 |
| Merck Index (14) | 1060 |
| MDL Number | MFCD00007968 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 99.0 % |
| Melting point | 127.0 to 130.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 128 °C |
| Boiling Point | 288 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | CU8700000 |
Transport Information:
| H.S.code* | 2924.29-000 |
Application
Benzamide: An Inhibitor of Poly (ADP-Ribose) Polymerase (PARP) Enzymes
Genomic instability is a hallmark of cancer and is often the result of altered DNA repair capabilities in tumor cells. Poly (ADP-ribose) polymerases (PARPs) are enzymes responsible for DNA damage detection and repair factor recruitment. PARP inhibitors are able to interact with the binding site for the PARP cofactor NAD+ and trap PARP on DNA, and induce cell death through replication stress-induced mitotic catastrophe. It has been reported that benzamide is a PARP inhibitor and has neuroprotective effects. (The product is for research use only.)
References
- Benzamide, an inhibitor of poly(ADP-ribose) polymerase, attenuates methamphetamine-induced dopamine neurotoxicity in the C57Bl/6N mouse
- Poly(ADP-ribose) polymerase inhibitors protect against MPTP-induced depletions of striatal dopamine and cortical noradrenaline in C57B1/6 mice
- Chapter 10, Clinical Development of the Nicotinamides and Benzamides Involving PARP as a Molecular Target (a review)
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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Other Documents
Related Products
Benzamide Zone Refined (number of passes:20)
| Product # | B0220 |
| CAS RN | 55-21-0 |
| Purity / Analysis Method: | >99.0%(HPLC) |