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CAS RN: 7770-78-7 | Product Number: A3117
(-)-Arctigenin
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Purity: >95.0%(GC)
Synonyms:
- (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
₩156,000
|
21 | 2 | It can be shipped in about 3-4 weeks after ordering | |
| 50MG |
₩466,100
|
≥40 | 8 | It can be shipped in about 3-4 weeks after ordering |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | A3117 |
| Purity / Analysis Method | >95.0%(GC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__4O__6 = 372.42 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 10MG-Glass Bottle with Plastic Insert (View image), 50MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 7770-78-7 |
| Reaxys Registry Number | 4206071 |
| PubChem Substance ID | 354335432 |
| MDL Number | MFCD00870597 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 95.0 % |
| Melting point | 98.0 to 102.0 °C |
| Specific rotation [a]20/D | -40.0 to -44.0 deg(C=1, methanol) |
Properties (reference)
| Melting Point | 100 °C |
| Specific Rotation | -42° (C=1,MeOH) |
| Maximum Absorption Wavelength | 280 nm (EtOH) |
GHS
Related Laws:
| RTECS# | LY9247000 |
Transport Information:
| H.S.code* | 2932.20-000 |
Application
Arctigenin: A Lignin with Wide Pharmacological Actions
Arctigenin and its glycoside, arctiin [A3118], are lignans found in many plants of Arctium lappa L. (AL, family Asteraceae)1). Arctigenin reportedly has wide pharmacological actions, such as antitumor2,3), anti-inflammatory4-6), and antiviral7,8), and anti-Alzheimer9) actions. (The product is for research purpose only.)
References
- 1)Isolation and identification of arctiin and arctigenin in leaves of burdock (Arctium lappa L.) by polyamide column chromatography in combination with HPLC-ESI/MS
- 2)Identification of Arctigenin as an Antitumor Agent Having the Ability to Eliminate the Tolerance of Cancer Cells to Nutrient Starvation
- 3)Arctigenin blocks the unfolded protein response and shows therapeutic antitumor activity
- 4)In vitro anti-inflammatory effects of arctigenin, a lignan from Arctium lappa L., through inhibition on iNOS pathway
- 5)Arctigenin inhibits lipopolysaccharide-induced iNOS expression in RAW264.7 cells through suppressing JAK-STAT signal pathway
- 6)Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages
- 7)(-)-Arctigenin as a Lead Structure for Inhibitors of Human Immunodeficiency Virus Type-1 Integrase
- 8)Therapeutic effect of arctiin and arctigenin in immunocompetent and immunocompromised mice infected with influenza A virus
- 9)Arctigenin effectively ameliorates memory impairment in Alzheimer's disease model mice targeting both β-amyloid production and clearance
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