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CAS RN: 55268-74-1 | Product Number: P2125
Praziquantel
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Purity: >98.0%(HPLC)(N)
Synonyms:
- 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
¥3,300
|
37 | ≥60 | Contact Us | |
| 25G |
¥11,400
|
21 | It can be shipped from Saitama warehouse on the same day* | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | P2125 |
Purity / Analysis Method 
|
>98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__9H__2__4N__2O__2 = 312.41 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 55268-74-1 |
| Reaxys Registry Number | 761557 |
| PubChem Substance ID | 253659951 |
| Merck Index (14) | 7716 |
| MDL Number | MFCD00058531 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 137.0 to 141.0 °C |
Properties (reference)
| Melting Point | 140 °C |
| Maximum Absorption Wavelength | 271 nm |
| Solubility in water | Insoluble |
| Degree of solubility in water | 0.4 g/l |
| Solubility (soluble in) | Methanol, Ethanol |
GHS
| Hazard Statements | H402 : Harmful to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
Related Laws:
| RTECS# | UQ4150000 |
Transport Information:
Application
Praziquantel: An Anthelmintic Agent for Schistosoma and Liver Fluke
Praziquantel (abbr.: PZQ), an anthelmintic agent, is used to treat schistosoma and liver fluke from 1980s. Although its mechanism of action remains unknown exactly, there are some reports that PZQ increases the permeability of the membranes of schistosoma cells towards calcium ions. PZQ thereby induces contraction of the schistosoma, resulting in paralysis in the contracted state.
References
- Praziquantel (a review)
- Resistance to praziquantel: direct evidence from Schistosoma mansoni isolated from Egyptian villagers
- PLGA nanoparticles containing praziquantel: effect of formulation variables on size distribution
- Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis
PubMed Literature
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