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CAS RN: 940310-85-0 | Product Number: N1099
NVP-BHG 712
×
Purity: >95.0%(HPLC)
Synonyms:
- 4-Methyl-3-[[1-methyl-6-(3-pyridinyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino]-N-[3-(trifluoromethyl)phenyl]benzamide
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 50MG |
¥19,800
|
9 | 4 | Contact Us |
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* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | N1099 |
Purity / Analysis Method 
|
>95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__6H__2__0F__3N__7O = 503.49 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 940310-85-0 |
| PubChem Substance ID | 354335680 |
| MDL Number | MFCD20272929 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Elemental analysis(Nitrogen) | 18.5 to 20.5 % |
| NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
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Application
NVP-BHG712: A Specific EphB4 Kinase Inhibitor
NVP-BHG712 has been reported as a specific EphB4 kinase inhibitor. EPHB4 is a member of the Eph family of receptor tyrosine kinases which play an important role in embryonic blood vessel development and vascular remodeling. Experimental evidence demonstrated tyrosine kinase EphB4 has been associated with tumor angiogenesis, growth and metastasis, thus making it a valuable and attractive target for drug design for therapeutic applications.
References
- The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis
PubMed Literature
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