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CAS RN: 110429-36-2 | Product Number: M2645
N-Methyl Paroxetine
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Purity: >98.0%(GC)(T)
Synonyms:
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
¥8,100
|
8 | It can be shipped from Saitama warehouse on the same day* | It can be shipped in about 2 weeks after ordering | |
| 1G |
¥27,300
|
4 | It can be shipped from Saitama warehouse on the same day* | It can be shipped in about 2 weeks after ordering |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
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* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | M2645 |
Purity / Analysis Method 
|
>98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__2__0H__2__2FNO__3 = 343.40 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 110429-36-2 |
| Reaxys Registry Number | 768178 |
| PubChem Substance ID | 253662337 |
| MDL Number | MFCD03788781 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 109.0 to 113.0 °C |
| Specific rotation [a]20/D | -69.0 to -89.0 deg(C=0.01, MeOH) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 111 °C |
| Specific Rotation | -70° (C=0.01,MeOH) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
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Application
N-Methyl paroxetine: A Synthetic Precursor of Paroxetine
N-Methyl paroxetine is a synthetic precursor of paroxetine hydrochloride hemihydrate [P1977] which is a 5-hydroxytryptamine (5-HT) uptake inhibitor.
References
- Preparation of crystalline paroxetine hydrochloride hemihydrate for use as an antidepressant
- R. D. Barnes, M. W. Wood-Kaczmar, J. E. Richardson, I. R. Lynch, P. C. Buxton, A. D. Curzons, Eur. Pat. Appl. 1987, EP 223403 A2.
- Preparation of paroxetine from N-alkyl derivatives.
- S.-z. Wang, Y. Matsumura, Eur. Pat. Appl. 1997, EP 810225 A1.
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