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CAS RN: 595-33-5 | Product Number: M1949
Megestrol Acetate

Purity: >96.0%(HPLC)
Synonyms:
- Megestrol 17-Acetate
- 17α-Acethoxy-6-methyl-4,6-pregnadiene-3,20-dione
- 17α-Hydroxy-6-methyl-4,6-pregnadiene-3,20-dione 17-Acetate
Product Documents:
Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
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---|---|---|---|---|---|
1G |
¥6,200
|
1 | It can be shipped from Saitama warehouse on the same day* | Contact Us | |
5G |
¥18,600
|
2 | 3 | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Product Number | M1949 |
Purity / Analysis Method | >96.0%(HPLC) |
Molecular Formula / Molecular Weight | C__2__4H__3__2O__4 = 384.52 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 595-33-5 |
Reaxys Registry Number | 1917291 |
PubChem Substance ID | 87560201 |
Merck Index (14) | 5805 |
MDL Number | MFCD00056470 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 96.0 area% |
Melting point | 213.0 to 220.0 °C |
Specific rotation [a]20/D | +9.0 to +13.0 deg(C=2, CHCl3) |
NMR | confirm to structure |
Properties (reference)
Melting Point | 218 °C |
Specific Rotation | 11° (C=2,CHCl3) |
Solubility (soluble in) | Chloroform |
GHS
Pictogram |
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Signal Word | Warning |
Hazard Statements | H351 : Suspected of causing cancer. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
RTECS# | TU4075000 |
Transport Information:
Application
Megestrol Acetate: A Semi-Synthetic Progestational Agent
Megestrol acetate and medroxyprogesterone acetate [M1964], semi-synthetic progestational agents, are effective hormonal treatments for metastatic breast cancer in postmenopausal women. The antineoplastic effect may result from inhibition of pituitary gonadotropin production and resultant decrease in estrogen secretion. Recently, megestrol acetate is often used for the treatment of anorexia and cachexia. The precise mechanism is unknown at the present time. (The product is for research purpose only.)
References
- Comparison of the antiandrogenic/androgenic activities of flutamide, cyproterone acetate and megestrol acetate
- An overview of megestrol acetate for the treatment of advanced breast cancer (a review)
- Cytokine activity in cancer-related anorexia/cachexia: role of megestrol acetate and medroxyprogesterone acetate (a review)
- Treating malnutrition with megestrol acetate: literature review and review of our experience (a review)
- Trace analysis of androgens and progestogens in environmental waters by ultra-performance liquid chromatography-electrospray tandem mass spectrometry
PubMed Literature
Articles/Brochures
TCIMAIL
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