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CAS RN: 465-99-6 | Product Number: H1645
Hederagenin
Purity: >98.0%(T)(HPLC)
Synonyms:
- 3β,4α-3,23-Dihydroxyolean-12-en-28-oic Acid
Product Documents:
Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH | Shipping Information |
---|---|---|---|---|---|
50MG |
¥15,400
|
1 | 18 | 20 | |
200MG |
¥50,700
|
14 | 5 | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
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* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Product Number | H1645 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__3__0H__4__8O__4 = 472.71 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container | 200MG-Glass Bottle with Plastic Insert (View image), 50MG-Glass Bottle with Plastic Insert (View image) |
CAS RN | 465-99-6 |
Reaxys Registry Number | 2711855 |
PubChem Substance ID | 354335220 |
Merck Index (14) | 4624 |
MDL Number | MFCD00017385 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
Specific rotation [a]20/D | +81.0 to +85.0 deg(C=1, Pyridine) |
Properties (reference)
Melting Point | 334 °C |
Maximum Absorption Wavelength | 405(H2SO4) nm |
GHS
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Application
Hederagenin: A Pentacyclic Triterpenoid with Many Biological Activities
Hederagenin is a pentacyclic triterpenoid. It is the aglycone part of numerous saponins found in Hedera helix, etc. and found in a variety of traditional medicines and food products. Reportedly, hederagenin and its glycosides (saponins) possess many biological activities such as anti-inflammatory1,2), antitumor3,4), antimutagenic5) and anticomplementary6) activities. Furthermore, hederagenin has been reported as a serotonin, norepinephrine and dopamine reuptake inhibitor.7) (The product is for research purpose only.)
References
- 1)Anti-inflammatory activities of hederagenin and crude saponin isolated from Sapindus mukorossi Gaertn
- 2)In vitro antiinflammatory activity of kalopanaxsaponin A isolated from Kalopanax pictus in murine macrophage RAW 264.7 cells
- 3)Hederagenin as a triterpene template for the development of new antitumor compounds
- 4)Kalopanaxsaponin A is a basic saponin structure for the anti-tumor activity of hederagenin monodesmosides
- 5)Essential moiety for antimutagenic and cytotoxic activity of hederagenin monodesmosides and bisdesmosides isolated from the stem bark of Kalopanax pictus
- 6)In vitro anticomplementary activity of hederagenin saponins isolated from roots of Dipsacus asper
- 7)The extracts of Fructus Akebiae, a preparation containing 90% of the active ingredient hederagenin: Serotonin, norepinephrine and dopamine reuptake inhibitor
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