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CAS RN: 301305-73-7 | Product Number: D5275
TCS 359
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Purity: >98.0%(HPLC)
Synonyms:
- 2-(3,4-Dimethoxybenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
- FLT-3 Inhibitor
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
¥15,500
|
3 | 2 | Contact Us | |
| 100MG |
¥46,500
|
9 | 6 | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | D5275 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__2__0N__2O__4S = 360.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Condition to Avoid | Light Sensitive,Heat Sensitive |
| CAS RN | 301305-73-7 |
| Reaxys Registry Number | 10482751 |
| PubChem Substance ID | 354334725 |
| MDL Number | MFCD00617269 |
Specifications
| Appearance | Light yellow to Brown powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 7.30 to 8.30 % |
| NMR | confirm to structure |
Properties (reference)
GHS
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Application
A Potent Inhibitor of Fms - Like Tyrosine Kinase 3 (FLT3)
It is reported that this compound exhibits potent inhibitory activity against the Fms - Like Tyrosine Kinase 3 (FLT3).1) For your information, FLT3 belongs to class III receptor tyrosine kinase family, and expresses on most acute leukemia cells. Therefore, several potent FLT3 inhibitors have been developed in recent years.2)
References
- 1)Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3
- 2)Quantifying the structural requirements for designing newer FLT3 inhibitors
PubMed Literature
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