Maximum quantity allowed is 999
Please select the quantity
CAS RN: 163252-36-6 | Product Number: C3845
Clevudine
×
![]()
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- 1-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
- 1-[(2S,3R,4S,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 250MG |
¥35,000
|
12 | It can be shipped from Saitama warehouse on the same day* | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
if you need further information.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | C3845 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__3FN__2O__5 = 260.22 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| Packaging and Container | 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 163252-36-6 |
| Reaxys Registry Number | 8153334 |
| MDL Number | MFCD00935785 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Volumetric Analysis) | min. 98.0 % |
| Melting point | 193.0 to 197.0 °C |
| Specific rotation | -107 to -117 deg(C=0.2, methanol) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 196 °C |
GHS
Related Laws:
| RTECS# | UV9052000 |
Transport Information:
Application
Clevudine: An L-Configuration Thymidine Analog with Antiviral Activity
Clevudine (L-FMAU; 2'-fluoro-5-methyl-β-L-arabinofuranosyluracil) is an unnatural L-configuration thymidine analog with potent anti-hepatitis B virus (HBV) activity in vitro and in vivo. There are reports that clevudine interferes with HBV replication by inhibiting the activity of viral DNA polymerase and reverse transcriptase. (The product is for research purpose only.)
References
- Use of 2'-fluoro-5-methyl-β-L-arabinofuranosyluracil as a novel antiviral agent for hepatitis B virus and Epstein-Barr virus
- Preclinical investigation of L-FMAU as an anti-hepatitis B virus agent (a review)
- Inhibitory effect of 2'-fluoro-5-methyl-beta-L-arabinofuranosyl-uracil on duck hepatitis B virus replication
- Clevudine: a potent inhibitor of hepatitis B virus in vitro and in vivo (a review)
- Nucleoside/nucleotide analog inhibitors of hepatitis B virus polymerase: mechanism of action and resistance (a review)
- Hepatitis B virus reverse transcriptase - Target of current antiviral therapy and future drug development (a review)
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.