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CAS RN: 100361-18-0 | Product Number: C2650
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
¥2,900
|
10 | It can be shipped from Saitama warehouse on the same day* | Contact Us | |
| 5G |
¥9,400
|
4 | 1 | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | C2650 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__2H__8ClFN__2O__3 = 282.66 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 100361-18-0 |
| Reaxys Registry Number | 4264924 |
| PubChem Substance ID | 354333349 |
| MDL Number | MFCD08458865 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 222.0 to 226.0 °C |
Properties (reference)
| Melting Point | 224 °C |
GHS
Related Laws:
Transport Information:
Application
Synthesis of 1-Cyclopropyl-1,8-naphthyridine Fluoroquinolone Antibacterials and Evaluations of their Antibacterial Activity
C2650 is an important intermediate for preparation of 1-cyclopropyl-1,8-naphthyridine fluoroquinolone antibacterials.
References
- Quinolone antibacterial agents. Synthesis and structure-activity relationships of 8-substituted quinoline-3-carboxylic acids and 1,8-naphthyridine-3-carboxylic acids
- Quinolone antibacterial agents. Synthesis and structure-activity relationships of a series of amino acid prodrugs of racemic and chiral 7-(3-amino-1-pyrrolidinyl)quinolones. Highly soluble quinolone prodrugs with in vivo pseudomonasactivity
- Novel Fluoroquinolone Antibacterial Agents Containing Oxime-Substituted (Aminomethyl)pyrrolidines: Synthesis and Antibacterial Activity of 7-(4-(Aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl -6-fluoro -4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic Acid (LB20304)
- Syntheses and biological evaluation of new fluoroquinolone antibacterials containing chiral oximinopyrrolidinea
- Synthesis and antibacteriala activity of novel fluoroquinolones containing substituted piperidines
- 4-Substituted 4-(1H-1,2,3-triazol-1-yl)piperidine: Novel C7 moieties of fluoroquinolones as antibacterial agents
PubMed Literature
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