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CAS RN: 85721-33-1 | Product Number: C2510
Ciprofloxacin
Purity: >98.0%(T)(HPLC)
Synonyms:
- 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid
Product Documents:
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* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | C2510 |
Purity / Analysis Method
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__1__8FN__3O__3 = 331.35 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 85721-33-1 |
| Reaxys Registry Number | 3568352 |
| PubChem Substance ID | 160871204 |
| SDBS (AIST Spectral DB) | 53251 |
| Merck Index (14) | 2314 |
| MDL Number | MFCD00185755 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 265 °C(dec.) |
| Solubility in water | Insoluble |
| Solubility (insoluble in) | Ethanol |
GHS
Related Laws:
| RTECS# | VB1993800 |
Transport Information:
Application
Biofilm research
By comparing the results by different biofilm quantitation techniques, effect of ciprofloxacin on biofilm formation in Staphylococcus aureus has been reported.1) According to the report, exposure to sub-minimum inhibitory concentration (sub-MIC) doses of ciprofloxacin showed to induce the biofilm-forming capacity of S. aureus via increasing the total biomass without affecting the bacterial growth of viable count.
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Antimicrobial Sub-MIC induces Staphylococcus aureus biofilm formation without affecting the bacterial count
- Ciprofloxacin-Loaded Mixed Polymeric Micelles as Antibiofilm Agents
- Sub-Inhibitory Concentrations of Ciprofloxacin Alone and Combinations with Plant-Derived Compounds against P. aeruginosa Biofilms and Their Effects on the Metabolomic Profile of P. aeruginosa Biofilms
- Evolution of Antibiotic Resistance in Biofilm and Planktonic Pseudomonas aeruginosa Populations Exposed to Subinhibitory Levels of Ciprofloxacin
- Subinhibitory concentration of ciprofloxacin targets quorum sensing system of Pseudomonas aeruginosa causing inhibition of biofilm formation & reduction of virulence
- Role of Antibiotic Penetration Limitation in Klebsiella pneumoniae Biofilm Resistance to Ampicillin and Ciprofloxacin
- Investigation of Ciprofloxacin Penetration into Pseudomonas aeruginosa Biofilms
- Comparison of the antibacterial activities of the quinolones Bay 12-8039, gatifloxacin (AM 1155), trovafloxacin, clinafloxacin, levofloxacin and ciprofloxacin
- Activity of acyclovir, ciprofloxacin and organotin polymers derived from acyclovir and ciprofloxacin against Herpes simplex virus (HSV-1) and Varicella Zoster virus (VZV)
- M. R. Roner, C. E. Carraher, Jr., A. Zhao, J. L. Roehr, K. D. Bassett, D. W. Siegmann-Louda, PMSE Prepr. 2004, 90, 515.
- Mechanism of inhibition of DNA gyrase by quinolone antibacterials: a cooperative drug-DNA binding model
- In vitro activity of Bay 09867, a new quinoline derivative, compared with those of other antimicrobial agents
Application
Quorum sensing research / Biofilm research
References
Application
Studies on the Antibacterial Activities of Ciprofloxacin
References
PubMed Literature
Documents
Product Articles
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Specifications
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