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CAS RN: 72956-09-3 | Product Number: C2260

Carvedilol


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
Product Documents:
5G
¥14,800
15   18   10  
25G
¥52,300
19   13   12  
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Product Number C2260
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__4H__2__6N__2O__4 = 406.48 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN 72956-09-3
Reaxys Registry Number 1514452
PubChem Substance ID 87560280
SDBS (AIST Spectral DB) 52170
Merck Index (14) 1873
MDL Number

MFCD00864692

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 115.0 to 119.0 °C
Properties (reference)
Melting Point 117 °C
Solubility in water Insoluble
Solubility (soluble in) Methanol
Solubility (slightly sol. in) Ethanol, Ether
GHS
Pictogram Pictogram
Hazard Statements H411 : Toxic to aquatic life with long lasting effects.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P273 : Avoid release to the environment.
P391 : Collect spillage.
Related Laws:
RTECS# UA8670000
Transport Information:
UN Number UN3077
Class 9
Packing Group III
Application
Carvedilol: A Nonselective β-Adrenoceptor Antagonist with α1-Receptor Antagonistic Activity

Carvedilol is a nonselective β1 and β2-adrenoceptor antagonist1) with α1-receptor antagonistic activity.2) The ratio of β12 adrenergic activity is 7:1,1) and the ratio of α:β adrenergic activity is 1:8.3) Carvedilol is a racemic mixture, and the β-adrenoreceptor blocking activity is present in the S-(-)-enantiomer and α1-adrenergic blocking activity is present in both R-(+) and S-(-)-enantiomers at equal potency.4) Carvedilol also has antioxidant and antiproliferative effects.5) Furthermore, carvedilol is able to stimulate β-arrestin-mediated signaling.6) (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
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