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CAS RN: 155206-00-1 | Product Number: B6165
Bimatoprost
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Purity: >98.0%(HPLC)
Synonyms:
- (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(S,E)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept-5-enamide
- 17-Phenyltrinor-PGF2α Ethylamide
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 5MG |
¥22,700
|
3 | 12 | Contact Us | |
| 25MG |
¥82,000
|
Contact Us | Contact Us | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | B6165 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__5H__3__7NO__4 = 415.57 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 155206-00-1 |
| Reaxys Registry Number | 9365461 |
| PubChem Substance ID | 468590953 |
| Merck Index (14) | 1221 |
| MDL Number | MFCD03411999 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +34.2 to +37.8 deg(C=1, MeOH) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 75 °C |
| Specific Rotation | 35° (C=1,MeOH) |
| Solubility (soluble in) | Ethanol, Methanol |
| Solubility (slightly sol. in) | Dimethylformamide |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | MJ8808000 |
Transport Information:
Application
Bimatoprost: A Synthetic Prostaglandin F2α (PGF2α) Analog with Unique Ocular Hypotensive Activity
Bimatoprost (AGN 192024) is a synthetic prostaglandin F2α (PGF2α) analog having pharmacological and biochemical properties district from PGF2α. PGF2α is formed from the endocannabinoid anandamide by a biosynthetic pathway involving cyclooxygenase-2 (COX-2). However, bimatoprost selectively mimics the effects of naturally occurring substances, prostamides. The target receptor for bimatoprost and the prostamides appears unique and unrelated to PG- and endocannabinoid-sensitive receptors. Although its mechanism of action is not completely understood, bimatoprost is believed to lower intraocular pressure (IOP) in humans by increasing outflow aqueous humor through both the trabecular meshwork and uveoscleral routes. In clinical, bimatoprost is used for the treatment of glaucoma. (The product is for research purpose only.)
References
- Pharmacological characterization of a novel antiglaucoma agent, bimatoprost (AGN 192024)
- Bimatoprost: A novel antiglaucoma agent (a review)
Documents
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